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NCT Number: NCT07446985

Is There a Benefit From Addition of Physical Exercise to Diet Restriction/Limitation in PCOS Women With Asthma?

Women with polysyctic ovarian syndrome (PCOS) usually develop many complications including asthma. Nowdays, diet restriction combimed with phsyical exercises may improve both problems

Recruiting

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Key information

Conditions

Polycystic Ovary Syndrome Adnexal Diseases Asthma Bronchial Diseases Cysts Endocrine System Diseases Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Genital Diseases Genital Diseases, Female Gonadal Disorders Hypersensitivity Hypersensitivity, Immediate Immune System Diseases Lung Diseases Lung Diseases, Obstructive Neoplasms Ovarian Cysts Ovarian Diseases Respiratory Hypersensitivity Respiratory Tract Diseases Urogenital Diseases

Age range

20 year–30 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

About this study

Forty Women with asthma with PCOS will be enrolled to be catogrized to Group I or group II. Group I will enroll twenty females with PCOS and asthma who will apply forty minutes walking on treadmill three times per week. Also Group I will follow low calorie diet and daily metformin for 12 weeks. Group II will will enroll twenty females with PCOS and asthma who will follow low calorie diet and daily metformin for 12 weeks

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • PCOS women
  • women with asthma
  • obese women (calss I)

Exclusion criteria

  • cardiac problems
  • renal problems
  • liver problems

Treatment and study plan

exercise plus limiitng diet

Behavioral

Group I will enroll twenty females with PCOS and asthma who will apply forty minutes walking on treadmill three times per week. Also Group I will follow low calorie diet and daily metformin for 12 weeks.

limiting diet

Behavioral

Group II will will enroll twenty females with PCOS and asthma who will follow low calorie diet and daily metformin for 12 weeks

Primary outcomes

  1. forced vital capcity

    Time frame: it will be measured after 12 weeks

    it is a pulmonary function testing

Secondary outcomes

  1. forced expiratory volume

    Time frame: It will be measured after 12 weeks

    it is a pulmonary function testing at the first second of expiration

  2. forced expiratory volume to forced expiratory capcity

    Time frame: It will be measured after 12 weeks

    it is a common ratio test in pulmonary function examiantions

  3. body mass index

    Time frame: It will be measured after 12 weeks

    it will be assessed on empty stomach and bladder

  4. waist circumference

    Time frame: it will be measured after 12 weeks

    it will be assessed at level of patient umblicus

  5. waist hip ratio

    Time frame: It will be measured after 12 weeks

    it is a measure of excess weight

  6. Mini asthma quality of life questionnaire

    Time frame: It will be measured after 12 weeks

    it is a questioanire assessing life quality in asthma

  7. scale of fatigue severity

    Time frame: It will be measured after 12 weeks

    it is a questionaire assesing fatigue

  8. luteinizing-hormone to follicle-stimulating-hormone ratio

    Time frame: It will be measured after 12 weeks

    it is an indicator on level of sex hormone production

  9. Testosterone

    Time frame: It will be measured after 12 weeks

    it is androgen hormone

  10. Dehydroepiandrosterone

    Time frame: It will be measured after 12 weeks

    it is a hormone that body naturally produces in the adrenal gland

Study contacts

Contact information is provided by the study sponsor or research team.

Ali MA Ismail, lecturer

CONTACT

[email protected]

01005154209

ali mohamed

CONTACT

[email protected]

0201031321109

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Mar 3, 2026
Registry last updated
Mar 3, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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