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NCT Number: NCT05277610

Iron Status and Lung Function in Pediatric Asthma

Iron has a variable role regarding asthma and respiratory function. In addition, iron deficiency may affect spirometry results in asthmatic children. So, we aimed to assess the effect of ion status on lung function in childhood asthma

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Key information

Conditions

Pulmonary Function Tests Anemia Anemia, Hypochromic Anemia, Iron-Deficiency Asthma Bronchial Diseases Hematologic Diseases Hemic and Lymphatic Diseases Hypersensitivity Hypersensitivity, Immediate Immune System Diseases Iron Deficiencies Iron Metabolism Disorders Lung Diseases Lung Diseases, Obstructive Metabolic Diseases Nutritional and Metabolic Diseases Respiratory Hypersensitivity Respiratory Tract Diseases

Age range

6 year–16 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Heba Omara

Cairo, Lecturer/Instructor, 11111111, Egypt

About this study

This cross-sectional study included fifty asthmatic children in the age group of 6-16 years. Asthmatic patients were classified according to their complete blood count and iron profile into 2 groups: group 1; asthmatic children without iron deficiency anemia (IDA), group 2; asthmatic children with IDA. All patients underwent full history taking, clinical examination, laboratory investigations, asthma control test, and pulmonary function tests.

Pulmonary function testing was performed using standardized spirometry. Lung function was measured by forced expiratory volume in one second (FEV1), forced vital capacity (FVC), FEV1/FVC, and maximal mid-expiratory flow (MMEF 25-75%) of FVC. both patients' groups are compared.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Confirmed diagnosis of bronchial asthma: The diagnosis of bronchial asthma in the studied children was based on clinical examination The diagnosis of iron deficiency anemia was supported by criteria provided and updated by the World Health Organization

Exclusion criteria

  • chronic lung diseases other than asthma Severe systemic illnesses such as liver, renal diseases, and nutritional disorders

Treatment and study plan

iron studies

Diagnostic Test

Pulmonary function testing was performed using standardized spirometry for asthmatic patients with iron deficiency anemia and those without iron deficiency anemia

Primary outcomes

  1. improved asthma control

    Time frame: 2 months

    higher asthma control test

Sponsors and collaborators

Lead sponsor

Ain Shams University

Other

Registry information

Official study title

Iron Status and Its Relation to Lung Function in Pediatric Asthmatics

Important dates

Study start
2019
Primary completion
2019
Study completion
2019
First posted
Mar 14, 2022
Registry last updated
Mar 14, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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