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Completed

NCT Number: NCT01431118

Iron Metabolism in Dragon Boat Athletes

The purpose of the study is:

* To investigate the effect of sport-specific stress in the iron metabolism of dragon boat athletes * To investigate the effects of sport-specific stress in the activity of pro-hepcidin and hepcidin

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Key information

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

This investigation evaluates the effects of sport-specific stress in iron metabolism of dragon boat athletes. Recent studies showed a significant increase in hepcidin activity under exercise (Röcker L. et al.(2005): Iron regulatory protein hepcidin is increased in female athletes after a marathon. European Journal of Applied Physiology, S. 95, 569-571)which possibly influences the iron metabolism.

In particular in this investigation the activity of pro-hepcidin and hepcidin under sport-specific stress is analysed. Therefore elite dragonboat athletes will be included to this study. Every athlete is tested once. At one exercise day from every athlete the iron metabolism especially the change of hepcidin, prohepcidin and iron before and after a specific dragonboat intervention is analysed.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • athletes performing dragon boat sport

Exclusion criteria

  • acute clinically significant intercurrent diseases

Treatment and study plan

specific dragon boating training intervention

Other

male athletes of the german national dragon boat team performing three specific training units at one day

specific dragon boat intervention

Other

women athletes of the german national dragon boat team performing two specific training units and one weight lifting test at one day

Primary outcomes

  1. change from Baseline in prohepcidin after performing dragonboating

    Time frame: pre and post exercise intervention at the same day

    one meassurement of prohepcidin immediate before and within three hours after performing two to four specific dragonboat interventions at the same day

Secondary outcomes

  1. haematocrit

    Time frame: pre and post exercise intervention at the same day

    one meassurement of haematocrit immediate before and within three hours after performing two to four specific dragonboat intervention at the same day

  2. value of reticulocytes

    Time frame: pre exercise

    one meassurement of reticulocytes immediate before performing two to four specific dragonboat interventions

  3. value of hypochromic erythrocytes

    Time frame: pre exercise

    one meassurement of hypochromic erythrocytes immediate before performing two to four specific dragonboat interventions

  4. change from Baseline in serum iron after performing dragonboating

    Time frame: pre and post exercise intervention at the same day

    one meassurement of serum iron immediate before and within three hours after performing two to four specific dragonboat interventions at the same day

  5. value of transferrin

    Time frame: pre exercise

    one meassurement of transferrin immediate before performing two to four specific dragonboat interventions

  6. value of transferrin saturation

    Time frame: pre exercise

    one meassurement of transferrin saturation immediate before performing two to four specific dragonboat interventions

  7. value of ferritin

    Time frame: pre exercise

    one meassurement of ferritin immediate before performing two to four specific dragonboat interventions

  8. change from Baseline in hepcidin after performing dragonboating

    Time frame: pre and post exercise intervention at the same day

    one meassurement of hepcidin immediate before and within three hours after performing two to four specific dragonboat interventions at the same day

Sponsors and collaborators

Lead sponsor

University of Giessen

Other

Collaborators

  • Deutscher Drachenboot Verband e.V.
  • MVZ für Laboratoriumsmedizin Koblenz

Registry information

Official study title

Iron Metabolism in Dragon Boat Athletes - An Analysis of Changes in Blood Count Parameters Under Sport-specific Stress

Important dates

Study start
2011
Primary completion
2012
Study completion
2012
First posted
Sep 9, 2011
Registry last updated
Jul 24, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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