the Outpatient Clinic of Pediatrics, Zagazig University Hospitals.
Zagazig, 055, Egypt
NCT Number: NCT05959122
Anemia is a major public health problem among preschool-aged children. The evidence demonstrated that early childhood anemia is a strong predictor of adulthood anemia (Gessner, 2009). According to Egypt's Demographic and Health Survey (EDHS), prevalence rates of anemia in children aged 6-59 months ranged from 23% to 45% (EDHS, 2014). It is assumed that 50% of the cases of anemia are due to ID (Aref and Khalifa, 2019). The major health problem in Egypt is ID that affects 41.2% of children aged <5years (El-Asheer et al., 2021). The total prevalence of IDA in the Nile Delta region was 17.19% of the children (El-Shanshory et al., 2021). Iron is a trace element that is essential to form hemoglobin in red blood cells and to carry oxygen to peripheral tissues. In addition, iron plays essential functions in the mitochondria, which are crucial for regulating energy metabolism in the skeletal muscle (Kang and Li, 2012). And low iron levels limit oxygen bioavailability in the peripheral tissues, including skeletal muscle (Jolly et al., 2001).Yu-mi et al., (2020) found a low handgrip strength in anemic patients. Also, ID can impaired brain energy metabolism, along with hypo-myelination and impaired dopamine signaling, is consistently described as one of the mechanistic causes of the neurodevelopmental deficits associated with early-life ID (Thomas et al., 2020).
HYPOTHESES:
There is a relation between IDA and pinch strength and hand dexterity in preschool children.
RESEARCH QUESTION:
Is there a relation between IDA and pinch strength and hand dexterity in preschool children?
The purpose of the current study is to find the relation between IDA and:
1. Pinch grip strength (tripod and tip to tip grip strength). 2. Hand dexterity in preschool children.
Looking for future studies?
Notify Me5 year–6 year
All sexes
Observational
Zagazig, 055, Egypt
i. Instrumentations for selection:
Updated 23/11/12
4
Inclusion criteria
<12 µg/L for children in absence of infection (WHO, 2017). ( Appendix I).
B. Exclusion Criteria:
Children will exclude if they have:
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
<12 µg/L for children in absence of infection (WHO, 2017). ( Appendix I).
Exclusion criteria
Other names: measure tip to tip and tripod pinch strength by Baseline mechanical Pinch gauge (0-60 lb.) and BOT-2 used to assess manual dexterity
Time frame: one year
Baseline mechanical Pinch gauge (0-60 lb.) used to measure tip to tip and tripod pinch strength for all participated children
Time frame: one year
Bruininks-Oseretsky Test of Motor Proficiency, Second Edition (BOT-2)
Time frame: one year
Fully automated blood cell counter (sysmex-Xs 800i) and AU 480-Chemistry auto-analyzer
Cairo University
Other
Acronym: IDA
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