Irbesartan in the Treatment of Hypertensive Patients With Metabolic Syndrome

Inclusion criteria

• Subjects must be willing and able to provide written informed consent. Subjects must read, sign, and receive a copy of the informed consent prior to any study procedures, including withdrawal of any antihypertensive medication.
• Males and females >= 18 years of age.
• Uncontrolled hypertension defined as an average systolic blood pressure >= 140 mmHg and/or an average diastolic blood pressure >= 90 mmHg. This applies to both people not taking any blood pressure medications and people taking just one blood pressure medication.
• Presenting at least 2 of the following:

• Obesity;
• High triglycerides;
• Low HDL cholesterol;
• Elevated fasting glucose.

Exclusion criteria

• Women of child bearing potential who are not using adequate birth control.
• Women who are pregnant or breastfeeding
• Diabetics
• Systolic blood pressure >= 180 mmHg.
• Diastolic blood pressure >= 110 mmHg.
• Stroke within past 12 months.
• Myocardial infarction and heart revascularization procedure or acute angina within past 6 months.
• Moderate to severe heart failure.
• Significant kidney or liver disease.
• Cancer in past 5 years.
• Drug or alcohol abuse.
• Gout
• Lupus