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Completed

NCT Number: NCT06767618

Investigation of Upper Extremity Functions in Patients With Rheumatoid Arthritis

There are limited studies in the literature evaluating upper extremity functional exercise capacity, muscle functions and daily living activities in rheumatoid arthritis patients. In this context, the aim of this study was to investigate upper extremity exercise capacity, hand grip strength and daily living activities in rheumatoid arthritis patients.

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Key information

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Kırşehir Ahi Evran University, Physical Therapy and Rehabilitation Center, Cardiopulmonary Unit

Kırşehir, Merkez, 40100, Turkey (Türkiye)

About this study

Rheumatoid arthritis is an inflammatory autoimmune chronic and systemic disease of unknown etiology. In addition to musculoskeletal involvement, lung involvement can also be observed in patients. Lung involvement and accompanying symptoms cause deterioration of physical function, quality of life and functional capacity. In rheumatoid arthritis, dyspnea can be observed during exertion due to disease progression, drug toxicity and respiratory/cardiovascular morbidities. In patients, decreased respiratory muscle strength, respiratory functions, carbon monoxide diffusion capacity and oxygen consumption also cause decreased physical functions. It has been reported that upper extremity exercise capacity and functional performance are reduced in patients with interstitial lung disease. It is known that peripheral muscle strength is an independent determinant of exercise capacity in interstitial lung disease. Rheumatoid cachexia, characterized by decreased muscle mass and increased fat mass, is observed in rheumatoid arthritis patients. Since the patients' accessory respiratory muscles are also affected, it can negatively affect their daily life activities, especially those that use the upper extremities.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Inclusion criteria

for patients with rheumatoid arthritis

  • Patients diagnosed with rheumatoid arthritis,
  • Between the ages of 18-75 years,
  • Patients who volunteer to participate in the study will be included in the study.

Exclusion criteria

Exclusion criteria

for patients with rheumatoid arthritis

  • Those with serious cardiopulmonary, neurological, neuromuscular, orthopedic and other systemic diseases or other diseases affecting physical functions,
  • Those who have participated in a planned exercise program in the last three months
  • Those with cognitive impairment that will cause difficulty in understanding and following exercise test instructions
  • Patients with contraindications for exercise testing or exercise training according to the American Sports Medicine Association will not be included in the study.

Treatment and study plan

Primary outcomes

  1. Evaluation of Upper Extremity Exercise Capacity

    Time frame: First day and second day

    The six minute peg board and ring test will be used to assess upper extremity exercise capacity.

  2. Glittre Activities of Daily Living

    Time frame: Second day

    The Glittre activities of Daily Living test will be used to evaluate the daily living activities of individuals.

Secondary outcomes

  1. Hand-grip strength

    Time frame: First day

    Hand-grip strength will be assessed using a hand dynamometer.

  2. Evaluation of upper extremity functional status

    Time frame: First day

    The Arm, Shoulder and Hand Disabilities Questionnaire (DASH) will be used to evaluate the upper extremity functional status of individuals. The DASH evaluates the functional status of the upper extremity subjectively according to the Likert scale. It consists of 3 sections. The questionnaire scores between 0 (no disability) and 100 (severe disability).

  3. Evaluation of arm and shoulder muscle strength and endurance

    Time frame: Second day

    The Thirty-Second Push-Up Test will be used to evaluate arm and shoulder muscle strength and endurance.

Sponsors and collaborators

Lead sponsor

Kirsehir Ahi Evran Universitesi

Other

Registry information

Official study title

Investigation of Upper Extremity Exercise Capacity, Hand Grip Strength and Daily Living Activities in Rheumatoid Arthritis Patients

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Jan 10, 2025
Registry last updated
May 13, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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