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OpenTrials
Completed

NCT Number: NCT04878523

Investigation of the Efficacies of Multi Berries Juice on Anti Oxidant Effect and Improvement of Skin Conditions

To assess multi berries juice on anti-oxidant effect and skin condition improvement

Completed

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Key information

Conditions

Skin Condition Anti Oxidative Stress Skin Diseases Skin and Connective Tissue Diseases

Age range

20 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Chia Nan University of Pharmacy & Science

Tainan, 71710, Taiwan

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy adults aged above 20 years old

Exclusion criteria

  • Subject who is not willing to participate in this study.
  • Patients with diseases of the skin, liver, kidney.
  • Subjects who have known cosmetic, drug or food allergies, difficulty in digestive tract absorption or disorder.
  • Female who is pregnant or nursing or planning to become pregnant during the course of the study.
  • Received facial laser therapy, chemical peeling or UV overexposure in the past 4 weeks.
  • Constant drug use

Treatment and study plan

multi berries juice

Dietary Supplement

Testing product

Other names: Sei Bella™ Pure Essence Whitening Multi-Berries Drink

Placebo drink

Dietary Supplement

Blank

Primary outcomes

  1. The change of skin UV spots

    Time frame: Change from Baseline skin UV spots at 8 weeks

    VISIA Complexion Analysis System was utilized to measure skin UV spots. Units: arbitrary units

  2. The change of skin melanin index

    Time frame: Change from Baseline skin melanin index at 8 weeks

    Soft Plus was utilized to measure skin melanin index. Units: arbitrary units

  3. The change of blood SOD content

    Time frame: Change from Baseline SOD content at 8 weeks

    Venous blood was sampled to measure concentrations of SOD

  4. The change of blood total antioxidant capacity (TAC)

    Time frame: Change from Baseline TAC at 8 weeks

    Venous blood was sampled to measure concentrations of TAC

  5. The change of skin L* value

    Time frame: Change from Baseline L* value at 8 weeks

    Chroma Meter MM500 was utilized to measure skin L* value. Units: arbitrary units, 0-100

  6. The change of skin spots

    Time frame: Change from Baseline skin spots at 8 weeks

    VISIA Complexion Analysis System was utilized to measure skin spots. Units: arbitrary units

  7. The change of skin brown spots

    Time frame: Change from Baseline skin brown spots at 8 weeks

    VISIA Complexion Analysis System was utilized to measure skin brown spots. Units: arbitrary units

Secondary outcomes

  1. The change of skin moisture

    Time frame: Change from Baseline skin moisture at 4 weeks

    Corneometer® CM825 was utilized to measure skin moisture. Units: arbitrary Corneometer® units 0-120

  2. The change of skin a* value

    Time frame: Change from Baseline a* value at 8 weeks

    Chroma Meter MM500 was utilized to measure skin a* value. Units: arbitrary units

  3. The change of skin elasticity

    Time frame: Change from Baseline skin elasticity at 8 weeks

    Soft Plus was utilized to measure skin elasticity. Units: arbitrary units

  4. The change of skin wrinkles

    Time frame: Change from Baseline skin wrinkles at 8 weeks

    VISIA Complexion Analysis System was utilized to measure skin wrinkles. Units: arbitrary units

  5. The change of skin texture

    Time frame: Change from Baseline skin texture at 8 weeks

    VISIA Complexion Analysis System was utilized to measure skin texture. Units: arbitrary units

  6. The change of skin pores

    Time frame: Change from Baseline skin pores at 8 weeks

    VISIA Complexion Analysis System was utilized to measure skin pores. Units: arbitrary units

  7. The change of skin collagen density

    Time frame: Change from Baseline skin collagen density at 8 weeks

    DermaLab® Series SkinLab Combo was utilized to measure skin collagen density. Units: arbitrary units

Other outcomes

  1. The change of total cholesterol of blood

    Time frame: Change from Baseline total cholesterol at 8 weeks

    Venous blood was sampled to measure total cholesterol

  2. The change of triglyceride of blood

    Time frame: Change from Baseline triglyceride at 8 weeks

    Venous blood was sampled to measure triglyceride

  3. The change of SGOT of blood

    Time frame: Change from Baseline SGOT at 8 weeks

    Venous blood was sampled to measure SGOT

  4. The change of SGPT of blood

    Time frame: Change from Baseline SGPT at 8 weeks

    Venous blood was sampled to measure SGPT

  5. The change of BUN of blood

    Time frame: Change from Baseline BUN at 8 weeks

    Venous blood was sampled to measure BUN

  6. The change of uric acid of blood

    Time frame: Change from Baseline uric acid at 8 weeks

    Venous blood was sampled to measure uric acid

  7. The change of creatinine of blood

    Time frame: Change from Baseline creatinine at 8 weeks

    Venous blood was sampled to measure creatinine

Sponsors and collaborators

Lead sponsor

TCI Co., Ltd.

Industry

Registry information

Important dates

Study start
2020
Primary completion
2021
Study completion
2021
First posted
May 7, 2021
Registry last updated
May 7, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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