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NCT Number: NCT07428161

Investigation of the Effects of Task-Oriented Circuit Training on Upper Extremity Motor Function in Stroke Patients

Stroke is a disease characterized by symptoms such as weakness on one side of the body, speech impairment or inability to understand spoken language, vision problems, and loss of balance, walking, and coordination, resulting from a disruption in cerebral circulation that prevents oxygenation and nourishment of brain tissue. Currently, treatment approaches that adopt motor learning principles after stroke are fundamentally based on motor learning, neural plasticity, biomechanics, and the systems model of motor control. Task-Oriented Training (TOT), one of these treatment approaches, is used in the physiotherapy process for neurological diseases, and there is significant clinical evidence regarding the benefits of TOT. While the effects of TOT in physiotherapy have been primarily studied on balance and walking, there are a limited number of studies examining its effects on upper extremity function. Task-Oriented Circuit Training (TOCT) is a task-oriented training program consisting of 15 exercise stations where task-oriented training is applied in the form of exercise stations. TOCT improved upper extremity skills in Parkinson's patients. However, no study examines its effects on stroke. Therefore, this study aims to examine the effects of TOCT on upper extremity motor functions and dual-task performance in stroke patients.

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Key information

Conditions

Stroke Brain Diseases Cardiovascular Diseases Central Nervous System Diseases Cerebrovascular Disorders Nervous System Diseases Vascular Diseases

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

About this study

This study is a randomized controlled study. The patients will be randomly divided into two groups exercise and control. Both groups will receive standard physiotherapy and rehabilitation exercises aimed at improving balance, gait, mobility, and upper extremity function, as well as standard occupational therapy exercises for the upper extremities. Additionally, the TOCT group will receive 18 one-on-one TOCT training sessions, 3 days a week, for 6 weeks. TOCT will be formed from daily life activities such as reaching out, grasping, writing, and manual skills, which are frequently used in daily life. As the outcome measures, disease severity, disability, and manual dexterity will be evaluated.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Having received a stroke diagnosis for the first time
  • Having received a stroke diagnosis at least 1 month ago
  • Being between 18-65 years of age

Exclusion criteria

  • Having the following degree of active joint movement in the wrist and fingers (These conditions are necessary for patients to have the minimum hand dexterity to perform TOCT exercises)
  • At least 20° extension starting from full flexion in the wrist
  • At least 10° extension or abduction in the thumb
  • At least 10° extension in the metacarpophalangeal and interphalangeal joints of the other fingers

Treatment and study plan

Exercise-TOCT

Other

Both groups will receive exercise-based training

Exercise- standard

Other

Standard occupational therapy exercises

Primary outcomes

  1. Manual dexterity performance - Baseline

    Time frame: Assessment will be conducted before the intervention

    Nine Hole Peg test (9-HPT)

  2. Manual dexterity performance - Post intervention

    Time frame: Assessment will be conducted immediately after the intervention

    Nine Hole Peg test (9-HPT)

  3. Finger and hand function - Baseline

    Time frame: Assessment will be conducted before the intervention

    Jebsen-Taylor Hand Function Test (JTHFT)

  4. Finger and hand function - Post intervention

    Time frame: Assessment will be conducted immediately after the intervention

    Jebsen-Taylor Hand Function Test (JTHFT)

  5. Upper extremity performance (coordination, dexterity and functioning) - Baseline

    Time frame: Assessment will be conducted before the intervention

    Action Research Arm Test (ARAT)

  6. Upper extremity performance (coordination, dexterity and functioning) - Post intervention

    Time frame: Assessment will be conducted immediately after the intervention

    Action Research Arm Test (ARAT)

  7. Grip muscle strength

    Time frame: Assessment will be conducted before the intervention

    Hand dynamometer

  8. Grip muscle strength

    Time frame: Assessment will be conducted immediately after the intervention

    Hand dynamometer

Study contacts

Contact information is provided by the study sponsor or research team.

Sefa Eldemir

CONTACT

[email protected]

+903462981916

Sponsors and collaborators

Lead sponsor

Gazi University

Other

Registry information

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Feb 23, 2026
Registry last updated
Feb 25, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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