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Completed

NCT Number: NCT05909371

Investigation of the Effects of Motor Cognitive Dual Task Exercises on Cognitive Function, Balance and Functional Capacity in Patients Who Have Undergone Liver Transplantation.

Liver transplantation is a life-saving treatment of choice for patients with acute or chronic liver failure. Liver transplantation is performed with a graft taken from a living donor or cadaver in patients with end-stage liver failure or who develop various complications regardless of the stage of the disease.In liver diseases, cognitive problems occur as well as physical problems. It has been observed that in some liver diseases, including hepatitis C, Wilson's disease, primary biliary cirrhosis, cognitive dysfunction that negatively affects the quality of life of patients, from mild cognitive problems to hepatic encephalopathy.

Our study will be carried out in Malatya İnönü University Turgut Özal Medical Center Liver Transplant Institute Hospital in order to investigate the effects of motor-cognitive dual-task exercises on cognitive function, balance and functional capacity in liver transplant patients.It will be divided into 2 groups as classical physiotherapy and motor-cognitive exercise. Classical physiotherapy and motor-cognitive exercise programs will be applied to the groups in accordance with the clinical characteristics of the individuals, tolerable, and in a standardized manner specific to the individuals. Evaluations will be made on the first day and at the end of the twenty-fourth session while the patient is in the service before starting the treatment.

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Key information

Conditions

Liver Transplantation

Age range

50 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Hasan Kalyoncu University

Gaziantep, 27000, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Be able to mobilize alone
  • Having performed a liver transplant over the age of 50
  • Spontaneous breathing
  • Being hemodynamically stable
  • Ability to read and write
  • Not having an orthopedic disability and functional capacity limitation
  • Being conscious and cooperative

Exclusion criteria

  • Not agreeing to participate in the study
  • Not continuing the treatment regularly
  • Having neurological or neuropsychiatric problems
  • Being colorblind

Treatment and study plan

Exercise

Other

Application of two different exercises to liver transplant individuals.

Primary outcomes

  1. Evaluation of Cognitive Functions

    Time frame: One day

    The Montreal Cognitive Assessment Scale will be used to evaluate cognitive functions. The score is between 0-30 points. In order to be considered as a cognitive disorder, the participant must get a score below 21 points.

  2. Evaluation of Cognitive Functions

    Time frame: One day before the rehabilitation

    The Montreal Cognitive Assessment Scale will be used to evaluate cognitive functions. The score is between 0-30 points. In order to be considered as a cognitive disorder, the participant must get a score below 21 points. A day before the rehabilitation

  3. Evaluation of Balance

    Time frame: One day before the rehabilitation

    Functional reach and timed get-go test were used for dynamic balance assessment, and single-leg standing tests were used for static balance assessment. A day before the rehabilitation

  4. Evaluation of Balance

    Time frame: One day

    Functional reach and timed get-go test were used for dynamic balance assessment, and single-leg standing tests were used for static balance assessment.At the time of discharge

  5. Assessment of functional capacity

    Time frame: One day before the rehabilitation

    In order to determine the functional capacity, a 6-minute walking test was applied. A day before the rehabilitation

  6. Assessment of functional capacity

    Time frame: One day

    In order to determine the functional capacity, a 6-minute walking test was applied.At the time of discharge

Sponsors and collaborators

Lead sponsor

Hasan Kalyoncu University

Other

Registry information

Official study title

Physiotherapy and Rehabilitation Doctoral Thesis Work

Important dates

Study start
2023
Primary completion
2023
Study completion
2024
First posted
Jun 18, 2023
Registry last updated
Jan 15, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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