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Completed

NCT Number: NCT07474597

Investigation of the Effectiveness of Myofascial Release Techniques Applied to the Popliteus Muscle in Individuals With Knee Pain.

This study aimed to evaluate the effectiveness of popliteus muscle-targeted myofascial release techniques (MFR) when added to conventional physical therapy and rehabilitation (PTR) and exercise protocols in patients with knee pain.

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Key information

Conditions

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

İstanbul Fatih Sultan Mehmet Eğitim ve Araştırma Hastahanesi

Istanbul, Turkey (Türkiye)

About this study

This study aimed to evaluate the effectiveness of popliteus muscle-targeted myofascial release techniques (MFR) when added to conventional physical therapy and rehabilitation (PTR) and exercise protocols in patients with knee pain. Sixty patients presenting with knee pain were assessed according to inclusion and exclusion criteria, and 45 eligible participants were enrolled. Participants were allocated into two groups: the popliteus group (23) and the control group (22). Assessments were performed before treatment and after treatment. Both groups received a standard PTR program consisting of heat therapy (20 min), transcutaneous electrical nerve stimulation (TENS) (20 min), therapeutic ultrasound (US) (4 min), and exercises, administered 5 days per week for a total of 10 sessions. In addition, popliteus muscle-targeted MFR techniques were applied to the popliteus group. Outcome measures included pain (visual analog scale, VAS), functional status (Western Ontario and McMaster Universities Osteoarthritis Index, WOMAC), quality of life (Short Form-12 Health Survey, SF-12), range of motion (ROM), limb circumference measurement, and balance tests (single-leg stance test, SLST).

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Being between 18-70 years of age
  • Being able to communicate in Turkish
  • Being literate
  • Having a diagnosis of non-specific knee pain, Patellafemoral pain syndrome, or Knee Osteoarthritis
  • Volunteering to participate in the study

Exclusion criteria

  • Having undergone surgery on the knee joint
  • Having a diagnosis of inflammatory rheumatism
  • Having a significant clinical infection
  • Having a fracture in the bones forming the knee joint
  • Having received cortisol treatment within the last 6 months
  • Having a disease that prevents the patient from lying prone
  • Having a history of deep vein thrombosis
  • Having severe varicose vein disease
  • Being an active cancer patient

Treatment and study plan

Myofascial Release

Other

Classical Myofascial Release

Primary outcomes

  1. Myofascial Release Techniques AppliMeasurement of quality of life in individuals with knee pain following myofascial release techniques applied to the popliteus muscle.

    Time frame: 5 days 10 sessions

    Measurement of quality of life in individuals with knee pain following myofascial release techniques applied to the popliteus muscle. The SF-12 scale was used as the measurement. Patella circumference measurements were also taken.

Sponsors and collaborators

Lead sponsor

Istanbul Rumeli University

Other

Registry information

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Mar 16, 2026
Registry last updated
Mar 17, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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