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OpenTrials
Completed

NCT Number: NCT04947397

Investigation of Pupillometry as Guide for Extubation Readiness in Anesthetized Children

Investigation of pupillometry as guide for extubation readiness in anesthetized children.

Completed

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Key information

Conditions

Anesthesia Laryngospasm on Emergence

Age range

2 year–10 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

UCSF Benioff Children's Hospital Oakland

Oakland, California, 94609, United States

About this study

Can a pupil metric be used to make extubation more safe in anesthetized children?

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Children undergoing general anesthesia and endotracheal intubation for surgery.
  • American Society of Anesthesiologists Physical Status Class I and II patients.

Exclusion criteria

  • Central nervous system abnormality.
  • Ophthalmologic abnormality.

Treatment and study plan

Pupillometry

Diagnostic Test

Pupillometry prior to extubation

Primary outcomes

  1. Extubation Success

    Time frame: Immediately after extubation

    Maintenance of spontaneous ventilation without pathologic airway response such as laryngospasm.

    Ventilation monitored in a standard manner, using chest wall movement, capnography, reservoir bag movement, condensation of anesthetic mask and auscultation.

Secondary outcomes

  1. Anesthetic Vapor Concentration at Extubation

    Time frame: At the time of extubation

    Percent of end-tidal sevoflurane at extubation

Other outcomes

  1. Breath-holding

    Time frame: Prior to extubation

    Measurement tool: Capnogram

Sponsors and collaborators

Lead sponsor

University of California, San Francisco

Other

Registry information

Important dates

Study start
2022
Primary completion
2023
Study completion
2023
First posted
Jul 1, 2021
Registry last updated
Jan 22, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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