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Completed

NCT Number: NCT04803617

Investigation of Pectoralis Muscle Strength in Elderly With Interstitial Lung Disease

Interstitial lung disease (ILD) is a restrictive lung disease characterized by impaired lung function, exercise limitation and skeletal muscle dysfunction. There is limited data on skeletal muscle function in ILD, most of which are focused on the lower limb muscles. The aim of this study were to evaluated the change of pectoralis muscle strength and relationship of pulmonary function with pectoralis muscle strength.

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Key information

Conditions

Interstitial Lung Disease Geriatric Hemic and Lymphatic Diseases Hypersensitivity Hypersensitivity, Delayed Idiopathic Pulmonary Fibrosis Immune System Diseases Lung Diseases Lung Diseases, Interstitial Lymphatic Diseases Lymphoproliferative Disorders Pulmonary Fibrosis Respiratory Tract Diseases Sarcoidosis Sarcoidosis, Pulmonary

Age range

65 year–85 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Giresun University

Giresun, Turkey (Türkiye)

About this study

This study consisted of intervention and control groups. Thirty one patients with ILD were included in the patient's group and 37 healthy volunteers in the control group. All participants were selected from the geriatric population. Demographic and cardiopulmonary physiotherapy assessment of all participants were performed. Lung function test, maximal inspiratory and expiratory pressure and pectoralis muscle strength were measured in participants of both groups. All measurements were performed once.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Diagnosed with ILD by a multidisciplinary team according to the 2011 ATS/ERS guidelines for ILD
  • Aged 65-85

Exclusion criteria

  • Uncontrolled/active cardiovascular, metabolic, systemic or cancerous disease
  • Significant orthopedic, neurologic or musculoskeletal comorbidity that limited functional independence
  • No being able to cooperate
  • Refuse to participate in the current study

Treatment and study plan

Assessment of pulmonary function and pectoralis muscle strength

Other

In both groups, forced vital capacity (FVC), forced expiratory volume in one second (FEV1) and FEV1 / FVC ratio were measured with portable spirometer according to the guidelines of the American Thoracic Society (ATS) and the European Respiratory Society (ERS). Maximal inspiratory (MIP) and expiratory pressure (MEP) were evaluated with mouth pressure device as per ATS/ERS guidelines. Sensation of dyspnea was assessed with Modified medical council research scale. Pectoralis muscle strength were measured isometrically using with digital hand held dynamometer.

Primary outcomes

  1. Pectoralis muscle strength test

    Time frame: 15 minute

    The pectoralis muscle strength were measured with handheld dynamometer in supine position. The shoulder joint of participant was positioned at 90º abducted and at 0º internal/external rotation and the elbow joint was flexed at 90º. The other shoulder joint was fixed by the physiotherapist. While the participant performed isometrically horizontal adduction movement, the measurement was performed on the distal part of the upper arm and the contraction was sustained for at least 5 seconds by the participant. The test was performed three times and with 60 seconds rest between tests. The mean of the best value on both sides was recorded.

Secondary outcomes

  1. FEV1

    Time frame: 5 minute

    FEV1 value was measured with portable spirometer according to ATS/ ERS guidelines for pulmonary function test. Results of the measurements were recorded as percentanges of predicted values.

  2. FVC

    Time frame: 5 minute

    FVC value was measured with portable spirometer according to ATS/ ERS guidelines for pulmonary function test. Results of the measurements were recorded as percentanges of predicted values.

  3. FEV1/FVC

    Time frame: 5 minute

    The ratio of FEV1/FVC was calculated by measuring device according to measured FEV1 and FVC values

  4. Respiratory muscle strength test

    Time frame: 15 minute

    Maximal mouth pressures were measured to evaluate respiratory muscle strength. The test was performed with mouth pressure device in sitting position. Participants breathed through a flanged mouthpiece inside the lips at near residual volume for the MIP value and near total lung capacity for MEP value . The maximum effort was sustained for at least one second. The test was repeated at least 3 times until no more than 10% difference was present between highest and previous measurements . The higest value and percentage value of predicted highest value were recorded

  5. Dyspnea assessment

    Time frame: 3 minute

    Modified Medical Council Research Dyspnea scale were used to assess sensation of dyspnea

Sponsors and collaborators

Lead sponsor

Habibedurdu

Other

Registry information

Official study title

The Effect of Pectoralis Muscle Strength on Pulmonary Function in Elderly With Interstitial Lung Disease

Important dates

Study start
2017
Primary completion
2017
Study completion
2017
First posted
Mar 17, 2021
Registry last updated
Mar 17, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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