Investigation of Genetic Disease Marker Associated With Spontaneous Haemorrhagic Stroke Complicating Severe Pre-eclampsia in Pregnancy

To search for a genetic marker of hemorrhagic stroke complicating severe eclampsia, a single nucleotide polymorphism (SNP) analysis of DNA obtained from the peripheral blood of patients with hemorrhagic stroke and normal control will be performed.

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Key information

Conditions

Hemorrhagic Stroke Brain Diseases Cardiovascular Diseases Central Nervous System Diseases Cerebrovascular Disorders Eclampsia Female Urogenital Diseases and Pregnancy Complications Hypertension, Pregnancy-Induced Nervous System Diseases Pregnancy Complications Stroke Urogenital Diseases Vascular Diseases

Age range

18 year–45 year

Sex eligibility

Female

Study type

Observational

Primary location

Hospital

Almaty, Kazakhstan

About this study

Detailed Description:

Unrelated Korean subjects who have Spontaneous hemorrhagic stroke complicating severe eclampsia in pregnancy were recruited in the current study. Genotyping for various SNP associated due to the linkage disequilibrium patterns is to be performed. Genotypes would be statistically compared between patients with hemorrhagic stroke and normal control subjects free of hemorrhagic stroke

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

-patients with hemorrhagic stroke complicating severe eclampsia in pregnancy

Exclusion criteria

patients without hemorrhagic stroke complicating severe eclampsia in pregnancy

Treatment and study plan

SNP analysis of the DNA

Genetic

SNP analysis of the DNA obtained from peripheral blood sample

Primary outcomes

genotyping for the SNP associated with hemorrhagic stroke complicating severe eclampsia in pregnancy

Time frame: 1 year

Sponsors and collaborators

Lead sponsor

Asfendiyarov Kazakh National Medical University

Other

Registry information

Official study title

Preventive and Personalized Medicine (2021-2023)

Important dates

Study start: 2021
Primary completion: 2023
Study completion: 2023
First posted: Nov 16, 2021
Registry last updated: Mar 14, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed