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OpenTrials
Completed

NCT Number: NCT02819128

Investigation of Endemic and Emerging Diseases in Populations of Homeless Households in Marseille.

Hypothesis:

Homeless people have infections not diagnosed with a potential impact on their health status.

Main Purpose: Improve the etiological diagnosis of endemic and/or emerging pathologies among homeless people.

Completed

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Key information

About this study

In Marseilles, the population of homeless is estimated at 1500 individuals, including 800 usually sleeping in the street, 600 in foster homes and a hundred in the structures of care. The precarious living conditions of homeless persons promote the emergence or re-emergence of many communicable infectious diseases homeless people whose symptoms are often overlooked by the subject and rarely established etiologic diagnosis.

Among these diseases, frequently described in the literature are infestation by lice and infectious diseases that they transmit (Bartonella quintana), skin infections, hepatitis E and C and finally the infection with Tropheryma Whipplei. In this study we propose to systematically in homeless subject an etiological diagnosis of pathogens at the origin of these diseases (i) to improve knowledge (ii) to improve their management, (iii) to limit the contagion.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Homeless Subject on the day of the study in one of two shelters for homeless Marseille ( Madrague City and Forbin )
  • Major subject ( > or equal to 18 years)
  • Freely about having signed the written informed consent,
  • About affiliated with a social security scheme

Exclusion criteria

  • Minor Subjects ( < 18 years )
  • Major subject under guardianship (L. 1121-8 )
  • Subject privated of freedom or under court order (L. 1121-6 )
  • Subject refusing to sign the informed consent form ,
  • Subject not affiliated with a social security insurance
  • Pregnant women , parturient or nursing (L. 1121-7 ) .

Treatment and study plan

Swabs skin, pharyngeal, and blood sample

Other

Collection of one blood sample with a volume of 10 mL (2 tubes of blood 5 mL ) and 2 swabs ( throat and skin ).

Collection of body lice

Other

For the subjects infested with body lice , if they want, their underwear will be recovered and sent to the laboratory to measure the resistance to permethrin.

Primary outcomes

  1. Percentage of subjects with an established microbiological diagnosis

    Time frame: 3 years

Secondary outcomes

  1. Prevalence of skin infections

    Time frame: 1 day

  2. Prevalence of Tropheryma whipplei infections

    Time frame: 1 day

  3. Prevalence of infestation by body lice

    Time frame: 1 day

  4. Percentage of body lice resistant to permethrin

    Time frame: 1 day

  5. Prevalence of infections by Bartonella quintana

    Time frame: 1 day

  6. Prevalence of infection by hepatitis E and C

    Time frame: 1 day

Sponsors and collaborators

Lead sponsor

Assistance Publique Hopitaux De Marseille

Other

Registry information

Acronym: SDF

Important dates

Study start
2014
Primary completion
2020
Study completion
2022
First posted
Jun 30, 2016
Registry last updated
Apr 21, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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