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OpenTrials
Completed

NCT Number: NCT01808027

Investigating Variation in Hospital Acute Coronary Syndrome Outcomes

To investigate the causes of hospital variation in outcomes from acute coronary syndromes in England and develop recommendations for improving patient care.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

University of Leeds

Leeds, West Yorkshire, LS2 9JT, United Kingdom

About this study

Over the last few years the chance of dying from a heart attack in England and Wales has reduced dramatically. Even so, there remain huge differences in mortality between hospitals. For example, up to a third of patients with a heart attack who attend hospitals in England are more likely to die than would be expected. That is, the type of treatment and the risk of death depends upon where a patient lives and which hospital they attend. In part, the variation in death may be due to the services available at the hospital or to factors such as socioeconomic deprivation. It may also relate to other factors such as depression, cardiac rehabilitation and whether patients take their medication after discharge from hospital. Using powerful statistical approaches that include measures of quality of life, we propose to examine data about heart attacks in England and investigate the 'postcode lottery of care'. Our aim, using regional data about heart attacks is to identify and measure the effects of hospital care. This research will identify hospital qualities that promote improved patient care. In doing so, best practice will be highlighted and healthcare policy changed so that all patients will have an equal chance of surviving a heart attack.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age > 18 years
  • Both sexes
  • Acute admission to the acute Trust with suspected acute coronary syndrome

Exclusion criteria

  • Patients at a terminal stage of any illness
  • Those in whom follow up would be inappropriate or impractical

Treatment and study plan

Primary outcomes

  1. delays to treatment

    Time frame: 12 months

    Quantification of hospital attributable effects relating to early and late mortality

Secondary outcomes

  1. Describing trajectories of quality of life recovery patterns

    Time frame: 12 month

    Describing trajectories of quality of life recovery patterns

Other outcomes

  1. Develop a risk score and a near-point risk Acute Coronary Syndrome model

    Time frame: two years

    Develop a risk score and a near-point risk Acute Coronary Syndrome model

Sponsors and collaborators

Lead sponsor

University of Leeds

Other

Registry information

Official study title

Evaluation of the Methods and Management of Acute Coronary Events: 3. Investigating Variation in Hospital Acute Coronary Syndrome Outcomes

Important dates

Study start
2011
Primary completion
2013
Study completion
2013
First posted
Mar 8, 2013
Registry last updated
Mar 8, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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