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Recruiting

NCT Number: NCT07388992

Investigating Specific Gait Patterns in Individuals Living With Multiple Sclerosis

The study aims to investigate specific ambulation patterns characteristic of the quality of gait in people with MS (pwMS)

Recruiting

Interested in participating?

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Key information

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

For people living with multiple sclerosis (pwMS):

  • Age at inclusion between =18 and =65 years old
  • Signed informed consent and ability to comply with study and follow-up.
  • Confirmed MS diagnosis according to McDonald criteria (2017)
  • Expanded Disability Status Scale EDSS = 6
  • Stable treatment for 2 months before inclusion (for both disease modifying and symptomatic therapies)
  • Ability and willingness to participate in and comply with all study procedures defined in the protocol
  • Subject will be eligible for enrollment in this study only if either affiliated to, or a beneficiary of a social security category

For Healthy volunteers :

  • Age at inclusion between =18 and =65 years old
  • Signed informed consent and ability to comply with study and follow-up.
  • Ability and willingness to participate in and comply with all study procedures defined in the protocol
  • Subject will be eligible for enrollment in this study only if either affiliated to, or a beneficiary of a social security category

Exclusion criteria

For pwMS:

  • Participants with a relapse within the past 3 months before the inclusion
  • Participants with significant cognitive disorders, limiting the understanding of the exercises to be performed or presence of apparent communication difficulties hindering the correct collection of data, as assessed by the investigator
  • Past or present pathology other than MS or surgery or trauma impacting gait, ambulatory function or upper limb function, as assessed by the investigator
  • Vulnerable adults: individuals subject to a legal protection measure (guardianship, limited guardianship, or judicial protection) or unable to express their consent.

For healthy volunteers (HV):

  • Participants with significant cognitive disorders, limiting the understanding of the exercises to be performed or presence of apparent communication difficulties hindering the correct collection of data, as assessed by the investigator
  • Past or present pathology or surgery or trauma impacting gait, ambulatory function or upper limb function, as assessed by the investigator
  • Vulnerable adults: individuals subject to a legal protection measure (guardianship, limited guardianship, or judicial protection) or unable to express their consent.

Treatment and study plan

Primary outcomes

  1. description of ambulation pattern in controlled environment in people living with multiple sclerosis (pwMS) with different disease severities

    Time frame: enrollment

    Measurement of daily life-like activity movements by Optical Motion Capture, pressure sensitive walkway and wearable sensors

Study contacts

Contact information is provided by the study sponsor or research team.

Ferial Toumi

CONTACT

[email protected]

+33 2 78 00 10 98

Sponsors and collaborators

Lead sponsor

SYSNAV

Industry

Registry information

Acronym: GAIT-MS

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Feb 5, 2026
Registry last updated
Mar 23, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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