Intrathecal Prilocaine and Adductor Canal Block vs Intrathecal Bupivacaine Alone for Ambulatory Knee Arthroscopy

- Although bupivacaine is safe and has a low rate of transient neurologic symptoms, the prolonged sensory and motor block is a drawback for day-case spinal anesthesia.Intrathecal hyperbaric prilocaine causes a much shorter motor block, with a similar onset time and lower inter-individual variability in motor block duration. Furthermore, the peripheral nerve block is used as an adjunct to the spinal anesthesia to prolong the surgical anesthetic conditions.

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Key information

Conditions

Post Operative Pain Neurologic Manifestations Pain Pain, Postoperative Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications Signs and Symptoms

Age range

21 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Ain-Shams University Hospitals

Cairo, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

American Society of Anesthesiologists (ASA) score I-II.
Body mass index < 35 kg/m2

Exclusion criteria

Patient's refusal.
Known coagulopathy.
Known peripheral neuropathy or neurological deficits.
Known allergy to study drugs.

Treatment and study plan

spinal anesthesia with hyperbaric prilocaine+adductor canal block (ACB) with bupivacaine

Drug

spinal anesthesia with hyperbaric prilocaine+adductor canal block (ACB) with bupivacaine

Spinal Anesthesia with Bupivacaine

Drug

spinal anesthesia with bupivacaine

Primary outcomes

The duration of motor block (minutes)

Time frame: 24 hours postoperatively

The duration of motor block (minutes)

Sponsors and collaborators

Lead sponsor

Ain Shams University

Other

Registry information

Official study title

Hybrid Anesthesia for Ambulatory Knee Arthroscopy Using Intrathecal Prilocaine and Adductor Canal Block vs Intrathecal Bupivacaine Alone: a Randomized Controlled Trial

Important dates

Study start: 2022
Primary completion: 2024
Study completion: 2024
First posted: Nov 8, 2022
Registry last updated: Nov 26, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed