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NCT Number: NCT06291389

Intraoperative Peak Airway Pressure Changes on Postoperative Pulmonary Function After Muscle Plication

An abdominal panniculus excision procedure is known as an abdominoplasty (panniculectomy). Musculofascial plication is a crucial aspect of abdominoplasty, especially for patients with significant divarication of the recti muscles. This study aimed to evaluate the effect of intraoperative changes in peak airway pressure (PAP) after muscle plication on postoperative pulmonary function.

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Key information

Conditions

Abdominal Compartment Syndrome Cardiovascular Diseases Compartment Syndromes Intra-Abdominal Hypertension Muscular Diseases Musculoskeletal Diseases Vascular Diseases

Age range

20 year–50 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Neveen Kohaf

Tanta, Egypt, 11865

Location status: Recruiting

Location contact

Ahmed Abosakaya

PRINCIPAL_INVESTIGATOR

Haney Bauiomy

PRINCIPAL_INVESTIGATOR

About this study

Musculofascial plication is a crucial aspect of abdominoplasty, especially for patients with significant divarication of the recti muscles. This surgical procedure involves the removal of surplus skin and fat around the abdomen, known as panneculectomy, and the anterior abdominal wall muscles' laxity being tightened. This study aimed to elucidate the effect of intraoperative changes in PAP after muscle plication on postoperative pulmonary function.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • age ranged between 20 and 50 years old,
  • American Society of Anesthesiologists (ASA) physical status classification I
  • came for abdominoplasty operation

Exclusion criteria

  • anemia or hemoglobin levels below 11g/dl
  • bleeding problems
  • cardiovascular disorders
  • restrictive and obstructive respiratory disease
  • abdominoplasty without plication.

Treatment and study plan

Primary outcomes

  1. Intraoperative peak airway pressure (PAP)

    Time frame: 4 hours

    Intraoperative peak airway pressure (PAP) will be observed Pre-plication, Post- plication in supine position and Post- plication in semi-sitting position

Secondary outcomes

  1. Duration of oxygen therapy

    Time frame: 1 week

    The duration of oxygen therapy will be recorded

  2. Post operative Tidal Volume (Vt) (Measured by spirometer)

    Time frame: 24 hours postoperatively

    The post operative Tidal Volume (Vt) will be measured by spirometer and will be recorded

  3. Post operative Respiratory Rate (RR)

    Time frame: 24 hours postoperatively

    The Post operative Respiratory Rate (RR) will be recorded

  4. Hospital stay.

    Time frame: 1 week

    The Duration of hospital stay will be recorded

Study contacts

Contact information is provided by the study sponsor or research team.

Neveen Kohaf, Ph.D

CONTACT

[email protected]

+201060383012

Sponsors and collaborators

Lead sponsor

Al-Azhar University

Other

Collaborators

  • Benha University

Registry information

Official study title

Effects of Intraoperative Peak Airway Pressure Changes on Postoperative Pulmonary Function After Muscle Plication in Abdominoplasty Operations: A Randomized Double-Blind Trial

Important dates

Study start
2024
Primary completion
2026
Study completion
2026
First posted
Mar 4, 2024
Registry last updated
Jan 6, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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