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OpenTrials
Completed

NCT Number: NCT06209034

Intraoperative Optic Nerve Sheath Diameter Changes After Laparoscopic Surgery

Laparoscopic surgery is a widely used alternative to open surgery; Advantages include reduced bleeding and pain intensity, shorter hospital stay, and improved cosmetic results.

Laparoscopic surgery involves the creation of a carbon dioxide (CO2) pneumoperitoneum to facilitate a clear surgical view, which can result in increased intracranial pressure (ICP).

Ultrasonographic measurement of optic nerve sheath diameter (ONSD) is a simple, non-invasive, yet reliable technique for ICP assessment.Ultrasonographic assessment of optic nerve sheath diameter (ONSD) has been proposed as a non-invasive measurement of intracranial pressure.

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Key information

Conditions

Optic Nerve Sheath Diameter Brain Diseases Central Nervous System Diseases Intracranial Hypertension Intracranial Pressure Increase Nervous System Diseases

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Kocaeli University, Kocaeli, Turkey (Türkiye)

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About this study

Ultrasonographic measurement of optic nerve sheath diameter (ONSD) is a simple, non-invasive, yet reliable technique for ICP assessment. Previous studies have demonstrated that ultrasonographic measurement of ONSD correlates with the degree of ICP and can detect intracranial hypertension in a variety of clinical settings.

It was planned to measure the optic nerve sheath throughout the surgery with the help of a linear ultrasound probe.

Ultrasonographically, in each measurement, the optic nerve sheath diameter (ONSD) was detected 3 mm behind the entry point of the optic nerve into the globe in both eyes. ONSD will be measured bilaterally 3 mm behind the papilla. It will be evaluated by transverse measurement for each optic nerve.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 18-75 aged patients
  • American Society of Anesthesiologists Classification (ASA) I-II-III patients
  • Patients undergoing laparoscopic surgery

Exclusion criteria

  • American Society of Anesthesiologists Classification (ASA) IV-V patients
  • Those with known ophthalmic disease
  • Those with a history of ophthalmic surgery
  • Those with any known neurological disorder
  • History of intracranial hypertension
  • Patients who will undergo open abdominal surgery

Treatment and study plan

Optic Nerve Sheath Measurement

Other

ONSD was measured bilaterally 3 mm posterior to the papilla. Transverse measurements were made for each optic nerve.

Primary outcomes

  1. Evaluation of optic nerve sheath diameter

    Time frame: During the operation

    Ultrasound measurement of optic nerve sheath diameter during laparoscopic surgery

Sponsors and collaborators

Lead sponsor

Kocaeli University

Other

Registry information

Official study title

Ultrasonographic Evaluation of Intraoperative Optic Nerve Sheath Diameter Changes in Patients Undergoing Laparoscopic Surgery

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
Jan 17, 2024
Registry last updated
Mar 18, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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