NCT Number: NCT07282899
Intraoperative Lung Protective Ventilation in Czech Republic
This questionnaire-based study aims to evaluate the adherence to and current clinical practices regarding intraoperative lung-protective ventilation (IOLPV) among anesthesiologists in the Czech Republic. Despite the established role of IOLPV in reducing postoperative pulmonary complications in selected populations, its routine application during general anesthesia for elective surgeries remains variable. The survey focuses on identifying common ventilation strategies, attitudes toward lung recruitment maneuvers, tidal volume selection, use of PEEP, and awareness of existing recommendations. The results will provide insight into national practice patterns, perceived barriers, and educational needs, helping to inform future guidelines, training initiatives, and efforts to enhance patient safety and postoperative outcomes across Czech anesthesia departments.
Trial opening soon.
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Conditions
Sex eligibility
All sexes
Study type
Observational
About this study
This study is designed as an observational cross-sectional survey focusing on attitudes, knowledge, and practical application of intraoperative lung-protective ventilation among anesthesiology professionals in the Czech Republic. The primary aim is to describe the prevalence of LPV-related practices during general anesthesia in adult surgical patients. Key elements of LPV include the use of lower tidal volumes adjusted to predicted body weight, titrated PEEP, avoidance of unnecessary high oxygen fractions, and a judicious approach to lung recruitment maneuvers. The study evaluates whether these components are routinely utilized and if so, under what clinical circumstances.
Secondary aims of the study include identifying barriers that may prevent anesthesiologists from applying LPV techniques, such as concerns about hemodynamic instability, limited training, lack of standardized protocols, insufficient monitoring capabilities, or doubts regarding clinical benefit. The survey also investigates how clinicians perceive the safety of recruitment maneuvers and whether they encounter adverse effects such as hypotension, desaturation, or barotrauma. The survey explores whether respondents view LPV as universally beneficial or applicable only to specific patient groups such as obese or critically ill individuals. The study further investigates whether national or departmental protocols and guidelines for ventilation exist at respondents' workplaces, whether ventilator settings are standardized, and whether institutional education or quality improvement initiatives support evidence-based ventilation.
The target population consists of anesthesiologists and anesthesiology trainees actively involved in perioperative care in hospitals across the Czech Republic. Participation is voluntary and anonymous, with no patient-level data collected. Demographic information such as level of training, years of experience, type of institution, and exposure to specialized perioperative or intensive care practice is included to allow subgroup comparisons. Data collection is conducted online via a secure electronic questionnaire with an estimated completion time of approximately five to eight minutes. The distribution strategy includes professional organizations, departmental mailing lists, and professional association communication channels to maximize nationwide representation.
The study utilizes a structured questionnaire composed of multiple-choice and ordinal-scale items that address five thematic categories: general anesthetic ventilation practices including tidal volume and FiO₂ selection; PEEP use and adherence to recommendations; indications and frequency of recruitment maneuvers; perceived safety and complications associated with LPV; and institutional culture, including guideline availability and ventilator technology. Respondents are asked to report how they usually manage typical elective surgical cases rather than unusual or high-risk scenarios, allowing insight into real-world standard practices. The results will quantify how closely routine clinical practice aligns with currently available scientific evidence and international perioperative ventilation recommendations.
The primary outcome is the proportion of respondents reporting ventilation settings that meet predefined LPV criteria in their routine practice. Secondary outcomes include differences in adherence between trainee and consultant anesthesiologists, between academic and non-academic hospitals, between centers with and without formal local protocols, and between clinicians with differing exposure to intensive care medicine. The data will be analyzed descriptively and comparatively to identify significant trends or variability within the national practice environment. Findings from this survey may provide a basis for future interventional or educational studies and facilitate development of nationwide recommendations.
The study is conducted in accordance with ethical research principles, including the Declaration of Helsinki and relevant European data protection regulations. Ethical approval is being obtained prior to survey initiation. Participation is fully voluntary, and no identifying personal data are collected; responses are recorded and analyzed only in aggregated form. No clinical intervention is performed, and therefore no additional risks to patients or participants are expected. The expected benefits of this research include improved understanding of current perioperative respiratory practices and identification of potential gaps where updated knowledge translation or institutional support may be necessary.
The overall purpose of this project is to contribute to improving perioperative patient outcomes by strengthening evidence-based ventilation strategies during general anesthesia. By highlighting current practice and potential challenges in implementation, the results can support targeted educational efforts, standardized national recommendations, and greater awareness of intraoperative pulmonary protection among Czech anesthesia providers. The data will also help position Czech clinical practice within the broader European context and may encourage future collaborative research initiatives focused on postoperative pulmonary complication reduction and enhanced quality of anesthesia care.
Who can participate
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- anaesthesiologist practiting in Czech republic
Exclusion criteria
- not lincensed anaesthesiologist
- anaesthesiologist outside Czech republic
Treatment and study plan
Primary outcomes
-
Adherence to IOLPV
Time frame: 20 days
Number of respondents that respond that meet IOLPV guidelines
Sponsors and collaborators
Lead sponsor
Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.
Other
Registry information
Official study title
Overview of Intraoperative Lung Protective Ventilation in Czech Republic
Acronym: IOLPVCZ
Important dates
- Study start
- 2026
- Primary completion
- 2026
- Study completion
- 2026
- First posted
- Dec 15, 2025
- Registry last updated
- Dec 15, 2025
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.