Hôpitaux Universitaires de Strasbourg
Strasbourg, 67091, France
Location status: Recruiting
Recruiting
NCT Number: NCT02246140
Intracranial Arterial Stenosis and Resin of Cannabis Use
There is an association between intracranial arterial stenosis and ischemic stroke in young adults. The aim of this study is to evaluate the prevalence of intracranial arterial stenosis in asymptomatic regular resin of cannabis users in comparison with control subjects.
Recruiting
Interested in participating?
Request InfoKey information
Conditions
Age range
18 year–45 year
Sex eligibility
All sexes
Study type
Interventional
Phase
Not applicable
Primary location
Who can participate
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- regular resin of cannabis users
Exclusion criteria
- taking vasoactive medications
- taking other illicit drugs
Treatment and study plan
Cerebral MRI and MRA
OtherPrimary outcomes
-
Presence of intracranial arterial stenosis on cerebral MRA
Time frame: 3 months
Rate on cerebral MRA the presence of cerebral Intracranial Arterial Stenosis segmental narrowing defined by at least two intra-cranial arteries compared with a cohort of non cannabis controls subjects.
Secondary outcomes
-
-Silent ischemic stroke on cerebral MRI
Time frame: 3 months
Evaluate on cerebral MRI the presence of sequelae of ischemic stroke defined by a parenchymal hyperintensity in a vascular territory defined on a T2 sequence.
-
-new intracranial arterial stenosis at 3 month follow-up
Time frame: 3 months
Evaluate a cerebral MRA at 3 months the presence of new intracranial stenosis among cannabis users, according to the prosecution or stopping use
-
-Reversibility of intracranial arterial stenosis at 3 month follow-up
Time frame: 3 months
Evaluate on cerebral MRA at 3 months reversibility stenosis present at T0 in cannabis users having stopped their consumption
Study contacts
Contact information is provided by the study sponsor or research team.
Sponsors and collaborators
Lead sponsor
University Hospital, Strasbourg, France
Other
Registry information
Official study title
Prevalence of Intracranial Arterial Stenosis in Regular Resin of Cannabis Users Compared to Control Subjects: a Preliminary Study of Feasibility
Important dates
- Study start
- 2014
- Primary completion
- 2026
- Study completion
- 2026
- First posted
- Sep 22, 2014
- Registry last updated
- Aug 8, 2025
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.