Froedtert Hospital
Milwaukee, Wisconsin, 53226, United States
Location status: Recruiting
Location contact
Eric Paulson, PhD
CONTACT
Eric Paulson, PhD
PRINCIPAL_INVESTIGATOR
PhD
CONTACT
Recruiting
NCT Number: NCT02344121
Intra- and Inter-fraction Changes in Radiation Therapy
Analysis to quantify intra-fraction, inter-fraction and post-treatment changes in tumor target volumes and surrounding normal organs in radiation therapy.
Recruiting
Interested in participating?
Request InfoKey information
About this study
The accurate and detailed knowledge of the changes (e.g., anatomically/biologically intra- and inter-fraction changes) to be obtained from this study would allow the research team to determine how Adaptive Radiation Therapy (ART) should be performed for a given tumor site/type. Radiation oncologists then can choose a proper ART strategy for a given tumor type to account for the anatomic/biological intra- and inter-fraction changes, improving accuracy of radiation therapy delivery, and in turn reducing treatment related toxicities and/or improving tumor local control.
Who can participate
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
°Completed radiation therapy
Exclusion criteria
°Subjects who refuse voluntary participation
Treatment and study plan
radiation therapy
RadiationRadiation therapy plans for cancer patients who have completed treatment.
Primary outcomes
-
Changes of volumes from baseline of organs at risk during and after radiation therapy.
Time frame: 2 years
Changes of organs at risk volumes (cm^3) during and after radiation therapy.
Secondary outcomes
-
Changes of volumes from baseline or tumors during and after radiation therapy.
Time frame: 2 years
Changes of tumor volumes (cm^3) during and after radiation therapy.
Study contacts
Contact information is provided by the study sponsor or research team.
Eric Paulson, PhD
CONTACT
Medical College of Wisconsin Cancer Center Clinical Trials Office
CONTACT
Sponsors and collaborators
Lead sponsor
Medical College of Wisconsin
Other
Registry information
Important dates
- Study start
- 2015
- Primary completion
- 2027
- Study completion
- 2028
- First posted
- Jan 22, 2015
- Registry last updated
- May 6, 2026
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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