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NCT Number: NCT07406373

Intra-abdominal Pressure, Abdominal Circumference, and Spinal Block Level in Cesarean Section

Spinal anesthesia is commonly used for cesarean section and provides effective anesthesia with rapid onset. However, the spread of spinal anesthesia may vary among pregnant women due to physiological and anatomical changes during pregnancy. Increased intra-abdominal pressure and abdominal circumference may influence cerebrospinal fluid dynamics and affect the level of sensory block achieved after spinal anesthesia.

This prospective observational study aims to evaluate the relationship between intra-abdominal pressure, abdominal circumference, and the maximum sensory block level following spinal anesthesia in pregnant women undergoing cesarean section. Intra-abdominal pressure and abdominal circumference will be measured before surgery, and sensory block levels and hemodynamic parameters will be assessed after spinal anesthesia. The findings of this study may help to better understand factors affecting spinal block spread in pregnant patients.

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Key information

Conditions

Cesarean Section Elective Cesarean Section Pregnancy

Age range

18 year–40 year

Sex eligibility

Female

Study type

Observational

Primary location

Kütahya Şehir Hastanesi

Kütahya, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Pregnant women aged 18-40 years
  • Scheduled for elective cesarean section at Kütahya City Hospital
  • Planned spinal anesthesia
  • ASA physical status II-III
  • Provided written informed consent

Exclusion criteria

  • Refusal to participate in the study
  • Emergency cesarean section
  • Preeclampsia or other hypertensive disorders of pregnancy
  • Onset of labor or premature rupture of membranes
  • Clinical conditions affecting intra-abdominal pressure, including peripheral edema or ascites
  • Height <140 cm or >180 cm
  • Body mass index < 40 kg/m²
  • Spinal deformity or history of spinal surgery
  • Contraindications to neuraxial anesthesia
  • Known allergy to bupivacaine
  • Requirement for additional surgical procedures other than cesarean section
  • Conditions contraindicating or interfering with intra-abdominal pressure measurement, including active or previous postdural puncture headache, neurogenic bladder, hematuria, or incidental abdominal mass

Treatment and study plan

Primary outcomes

  1. Maximum sensory block level after spinal anesthesia

    Time frame: Within the first 30 minutes after spinal anesthesia

    The maximum dermatomal level of sensory block assessed by loss of cold sensation after spinal anesthesia.

Secondary outcomes

  1. Intra-abdominal pressure

    Time frame: Baseline (preoperative, before spinal anesthesia) and early postoperative period (within 30 minutes after cesarean section)

    Intra-abdominal pressure measured in the preoperative period before spinal anesthesia and in the postoperative period following cesarean section using an intravesical measurement technique.

  2. Abdominal circumference

    Time frame: Baseline (preoperative, before spinal anesthesia) and early postoperative period (within 30 minutes after cesarean section)

    Abdominal circumference measured at the level of the umbilicus before spinal anesthesia and in the postoperative period following cesarean section.

  3. Incidence of hypotension after spinal anesthesia

    Time frame: Within the first 30 minutes after spinal anesthesia

    Hypotension defined as mean arterial pressure <65 mmHg measured during the first 30 minutes after spinal anesthesia.

  4. Vasopressor requirement

    Time frame: Perioperative period

    Requirement and total dose of vasopressor agents administered after spinal anesthesia.

Sponsors and collaborators

Lead sponsor

Kutahya Health Sciences University

Other

Registry information

Official study title

The Effect of Intra-abdominal Pressure and Abdominal Circumference on Sensory Block Level After Spinal Anesthesia in Pregnant Women Undergoing Cesarean Section

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Feb 12, 2026
Registry last updated
May 1, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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