Skip to main content
OpenTrials
Active, Not Recruiting

NCT Number: NCT07267936

Interventions for Maximizing Patient And Family Smoking Cessation Together

This feasibility study evaluates the effectiveness of a household-based smoking cessation intervention for patients and their household members. Patients who smoke and live with household members who also smoke will be invited to participate in the Treating Tobacco Dependency (TTD) program at Royal Papworth Hospital. The study aims to assess whether providing support to both patients and their household members improves quit rates and reduces relapse risk.

Participants will receive nicotine replacement therapy (NRT) and behavioural support, with follow-up assessments at 28 days, 3 months, and 12 months after starting the program. This study will compare outcomes to historical data from patients who participated in the TTD program without household support.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Notify Me

Key information

Conditions

Smoking Cessation Behavior Health Behavior

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Royal Papworth Hospital NHS Foundation Trust

Cambridge, Cambridgeshire, CB2 0AY, United Kingdom

About this study

The Treating Tobacco Dependency (TTD) program is currently available at Royal Papworth Hospital as part of an NHS initiative that started in August 2023. The program is available to all patients who smoke tobacco and are admitted to the hospital for at least 24 hours.

The TTD program provides NRT and behavioural counselling support, initially delivered by the TTD team at Royal Papworth Hospital, followed by HealthyYou, an NHS-approved stop smoking organization. Through this study, investigators are extending the invitation to household members of Royal Papworth Hospital patients to join the TTD program. This will allow the research team to assess whether a household-based intervention improves smoking cessation rates for both patients and their household members.

All participants will be followed up at 28 days, 3 months and 12 months post start of quit smoking. The smoking cessation rate will be compared to the routine TTD data set the research team has previously collected over the last year before household members were approached. This data will be acting as a control.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Any inpatient aged 18 and above admitted to Papworth Hospital who smoke. (Smoking is described as using any tobacco products as defined by the TTD programme)
  • Patient and household members must be eligible to join the TTD programme.
  • Patients must live in a household with other smokers.
  • Participants must live in Cambridgeshire and/or be registered with a GP Practice in the Cambridgeshire & Peterborough Integrated Care System

Exclusion criteria

  • Pregnant individuals - Pregnant individuals who smoke are offered a differing pathway to the standard TTD programme.
  • Contraindications for NRT.
  • Any household member who smokes unwilling to participate.
  • Individuals already enrolled on smoking cessation programme.

Treatment and study plan

Household member support

Other

The intervention in this study involves inviting household members of the patients, to participate in the Treating Tobacco Dependency program.

Primary outcomes

  1. Quit Rate among patients at 28 days

    Time frame: 28 days

    Assess difference in quit rates between patients with household support and the control group at 28 days.

Secondary outcomes

  1. Patient relapse rate

    Time frame: 3 and 12 months

    Patient relapse rate at 3 and 12 months.

  2. Household member quit rate

    Time frame: 28 days, 3 months and 12 months

    Household member quit rate at 28 days, 3 months and 12 months.

  3. Difference in relapse rate between patients with and without household members support

    Time frame: 3 months and 12 months

    Difference in relapse rates between the two groups at 3 months and 12 months (Patients supported with household members and the control group)

  4. Acceptance rate of support among household members

    Time frame: Baseline (At the time of screening , prior to enrollment)

    Potential household members who were approached but did not agree to participate in the study will be analyzed for the Acceptance of Support Among Household Members Who Smoke (%) endpoint

Sponsors and collaborators

Lead sponsor

Papworth Hospital NHS Foundation Trust

Other Gov

Registry information

Acronym: IMPACT

Important dates

Study start
2025
Primary completion
2026
Study completion
2027
First posted
Dec 5, 2025
Registry last updated
May 14, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.