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Completed

NCT Number: NCT00733941

Interval Training in Young Healthy Individuals

Individuals who participate in regular physical exercise possess a lower prevalence of cardiovascular risk factors such as hypertension, type 2 diabetes, obesity and hypercholesterolemia, and aerobic exercise is therefore considered an important adjuvant therapy in risk factor modification and to promote health.

The main focus of the present study is therefore to detect how rapid it is possible to increase aerobic capacity with interval running exercise.

The hypothesis is that it is possible to improve maximal oxygen uptake faster when increasing training frequency. The total gain in maximal oxygen uptake will however be the same between the two groups when they have performed the same amount of training

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Key information

Conditions

Healthy Subjects Exercise Test

Age range

18 year–27 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

NTNU, Trondheim, Norway

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About this study

We will perform aerobic interval training at an intensity of 90-95% of maximum heart rate in healthy individuals. The subjects will be randomly assigned to carry out a total of 24 exercise-sessions, either at 3 times per week or 8 times per week.

The two groups will carry out 24 training sessions before 8 weeks of detraining will provide how rapidly aerobic capacity is lost due to inactivity. After the detraining period a retraining phase is introduced to detect if improvements in aerobic capacity occur more rapidly compared to before the first training period

The subjects will be tested for oxygen uptake, pumping capacity of the heart, blood volume, skeletal muscle enzyme activity, endothelial function.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • BMI<27, non-smokers, train less that 1-2 times per week, VO2max <60 for male and <50 for female.

Exclusion criteria

  • Hypertension, diabetes and cardiovascular disease.

Treatment and study plan

High frequency training

Behavioral

24 training sessions, 8x weekly, followed by detraining phase 8 weeks, and retraining

normal frequence training

Behavioral

24 training sessions, 3x weekly, followed by detraining phase 8 weeks, and retraining

Primary outcomes

  1. Oxygen uptake

    Time frame: Before and after the training-, detraining- and retraining-phase

Secondary outcomes

  1. Cardiac function and skeletal muscle enzyme activity

    Time frame: After training, detraining and retraining

Sponsors and collaborators

Lead sponsor

Norwegian University of Science and Technology

Other

Registry information

Official study title

Interval Training: Training, Detraining and Retraining; an Interventional Study

Important dates

Study start
2008
Primary completion
2009
Study completion
2009
First posted
Aug 13, 2008
Registry last updated
May 27, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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