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Completed

NCT Number: NCT02635152

Interpretation Bias Modification for Body Dysmorphic Disorder

The purpose of this study is to determine whether a computerized intervention designed to reduce appearance and evaluation related interpretation biases will reduce symptoms associated with body dysmorphic disorder.

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Key information

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Florida State University Psychology Department

Tallahassee, Florida, 32304, United States

About this study

The present study aims to examine the feasibility of a remote treatment for body dysmorphic disorder delivered via the Internet. To evaluate the efficacy of the IBM protocol we have developed in reducing negative appearance and evaluative related interpretations, we will conduct a two-arm randomized controlled trial over the internet. Individuals with a diagnosis of body dysmorphic disorder (N = 40) will be randomized to one of two conditions: 1) IBM or 2) progressive muscle relaxation. Each condition will consist of eight 10-25 minute treatment sessions. Participants will complete two sessions per week for four weeks and will be administered assessments at pre-treatment, one week post-treatment and at 3-month follow-up. We hypothesize that: 1) IBM will lead to greater reductions in BDD symptoms than the PMR condition; 2) IBM will lead to greater reductions in depression, anxiety and suicidal ideation than the PMR condition; 3) IBM will lead to greater reductions in threat interpretations and greater increases in benign interpretations than the PMR condition; 4) The effects of condition on BDD symptoms will be mediated by changes in BDD-related interpretation bias; and 5) The effects of training in the IBM condition will be maintained at the 3-month follow-up assessments.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Current diagnosis of Body Dysmorphic Disorder according to DSM-5 criteria
  • BDD-YBOCS score greater than or equal to 20
  • Fluent in English
  • No significant physical defect or flaw in appearance (e.g., disfiguration)

Exclusion criteria

  • History of psychotic disorder, bipolar disorder, borderline personality disorder
  • Current substance use disorder
  • Unstable medication status (i.e. change in medication within the last month)
  • Concurrent psychotherapy for appearance concerns
  • Active and clinically significant suicidality

Treatment and study plan

Interpretation Bias Modification

Behavioral

Eight 10-25 minute sessions of interpretation modification to reduce negative interpretation biases related to appearance.

Progressive Muscle Relaxation

Behavioral

Eight 15-minute sessions of progressive muscle relaxation (PMR).

Primary outcomes

  1. Yale-Brown Obsessive Compulsive Scale Modified for Body Dysmorphic Disorder (BDD-YBOCS; Phillips et al., 1997)

    Time frame: change from baseline at one-week post treatment and 3-months post-treatment

    Measures past-week BDD symptom severity

Secondary outcomes

  1. Beck Depression Inventory (BDI-II; Beck, Steer, & Brown, 1996)

    Time frame: change from baseline at one-week post treatment and 3-months post-treatment

    Measures depressive symptom severity

  2. Beck Anxiety Inventory (BAI; Steer & Beck, 1997)

    Time frame: change from baseline at one-week post treatment and 3-months post-treatment

    Measure anxious symptom severity

  3. Depressive Symptom Index-Suicidality Subscale

    Time frame: change from baseline at one-week post treatment and 3-months post-treatment

    Measure severity of recent suicidality

  4. Body Dysmorphic Disorder Word Sentence Association Paradigm (BDD-WSAP; modified from Hindash & Amir, 2011)

    Time frame: change from baseline at one-week post treatment and 3-months post-treatment

    Measure of strength of BDD-related (i.e. evaluation- and appearance- related threat interpretation biases)

Sponsors and collaborators

Lead sponsor

Florida State University

Other

Registry information

Official study title

Evaluation of an Internet-Based Treatment for Body Dysmorphic Disorder

Important dates

Study start
2015
Primary completion
2018
Study completion
2018
First posted
Dec 18, 2015
Registry last updated
Jan 29, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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