Interpersonal Psychotherapy for Depressed Adolescents and Parents

The purpose of this study is to examine the feasibility and acceptability of an adaptation of Interpersonal Psychotherapy for Depressed Adolescents (IPT-A) that includes greater and more structured involvement of the parents in the treatment.

Completed

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Key information

Conditions

Major Depression Adjustment Disorders Depressive Disorder Depressive Disorder Not Otherwise Specified Depressive Disorder, Major Dysthymic Disorder Mental Disorders Mood Disorders Trauma and Stressor Related Disorders

Age range

12 year–18 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 1

About this study

Adolescent depression is a significant public health problem, and it increases the risk of poor psychosocial outcomes in adolescence and adulthood. Interpersonal Psychotherapy for Depressed Adolescents (IPT-A) has been found to be an effective treatment for reducing adolescents' depressive symptoms and improving their global and social functioning. The purpose of the current study is to examine the feasibility and acceptability of IPT-A when it is delivered with greater and more structured involvement of the parents in the treatment.

Participants will receive 15 weeks of Interpersonal Psychotherapy for Depressed Adolescents and Parents (IPT-AP). Eight the therapy sessions are conducted with the adolescent individually, two are with the parent(s) individually, and five are conducted with the adolescent and parent(s) together. At the end of the 15 weeks, participants who have demonstrated at least a 50% reduction in depressive symptoms will participate in three booster sessions delivered on a monthly basis. All participants will be assessed at baseline, week 5, week 10, week 15 (post-treatment), and 3 months post-treatment to measure depressive symptoms, global and social functioning, and attitudes toward treatment.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Meets diagnostic criteria for major depression, dysthymic disorder, depressive disorder not otherwise specified, or adjustment disorder with depressed mood
Score between 10 and 28 on the HRSD
Score of 65 or less on the C-GAS
English-speaking adolescent
Parental or legal guardian consent to participate

Exclusion criteria

Actively suicidal
Score greater than 28 on the HRSD
Mentally retarded
Meets diagnostic criteria for current substance abuse, schizophrenia, bipolar disorder, psychosis, conduct disorder, or eating disorder
Currently in active treatment for depression
Taking antidepressant medication at the time of baseline assessment
Medical illness likely to complicate or interfere with treatment
Victim of ongoing or previously undisclosed child abuse
Parent psychiatrically hospitalized within the past 3 months

Treatment and study plan

Interpersonal Therapy for Depressed Adolescents & Parents

Behavioral

15 weekly psychotherapy sessions

Primary outcomes

Clinical Global Improvement (CGI), Hamilton Rating Scale for Depression (HRSD), Center for Epidemiological Studies - Depression Scale (CES-D)

Time frame: baseline, week 5, 10, 15

Secondary outcomes

Global Assessment Scale for Children (C-GAS), Social Adjustment Scale - Self-report (SAS-SR), Conflict Behavior Questionnaire (CBQ-20), Observational assessment of parent-adolescent communication

Time frame: baseline, week 5, 10, 15

Sponsors and collaborators

Lead sponsor

New York State Psychiatric Institute

Other

Collaborators

Columbia University

Registry information

Official study title

An Open Clinical Trial of Interpersonal Psychotherapy for Depressed Adolescence and Parents

Important dates

Study start: 2007
Primary completion: 2009
Study completion: 2009
First posted: Feb 21, 2008
Registry last updated: Mar 9, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed