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Completed

NCT Number: NCT00845260

Internet-Versus Group-Administered Cognitive Behavior Therapy for Panic Disorder

Panic Disorder with or without agoraphobia (PD/A) is a common, and unless it is treated, often chronic psychiatric disorder. The are effective pharmacological as well as psychological treatments for PD/A. Because of the lack of availability of the most effective psychological treatment, cognitive behavior therapy (CBT), self-help based CBT treatments have been developed. One of those are Internet-based CBT. The aim of this study is to compare the effectiveness of Internet and group CBT for PD/A in a regular psychiatric setting. 113 patients are consecutively and randomly assigned to either treatment (both lasting 10 weeks). The main outcome measure is the Panic Disorder Severity Scale(PDSS). The study hypothesis is that treatments will show equal effectiveness.

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Key information

Conditions

Panic Disorder Anxiety Disorders Mental Disorders

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 3

Primary location

Karolinska Institutet, Department of Clinical Neuroscience, Section of psychiatry, Karolinska Hospital Solna R5

Stockholm, 171 76, Sweden

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Primary Panic Disorder with or without Agoraphobia (PD/A)

Exclusion criteria

  • active substance abuse
  • physiological etiology of panic symptoms
  • under 18 years of age
  • severe depression or suicidal ideation.
  • if on drugs for PD, not having had a constant dosage for 2 months
  • undergoing other cognitive behavioral treatment

Treatment and study plan

Internet-based cognitive behavior therapy (CBT).

Behavioral

Self-help program and guidance by psychologist via e-mail during 10 weeks.

Group CBT

Behavioral

Group cognitive behavior therapy (CBT) during 10 weeks.

Primary outcomes

  1. Panic Disorder Severity Scale (PDSS)

    Time frame: Pre, post at 6-month follow-up

Secondary outcomes

  1. Montgomery-Åsberg Depression Rating Scale (MADRS) Anxiety Sensitivity Index (ASI) Sheehan Disability Scale (SDS)

    Time frame: Pre, post and 6-month follow-up

Sponsors and collaborators

Lead sponsor

Karolinska Institutet

Other

Collaborators

  • Region Stockholm

Registry information

Official study title

Internet- Versus Group-Administered Cognitive Behavior Therapy for Panic Disorder in a Psychiatric Setting: A Randomized Equivalence Trial

Acronym: IP2

Important dates

Study start
2004
Primary completion
2007
Study completion
2007
First posted
Feb 18, 2009
Registry last updated
Feb 18, 2009

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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