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NCT Number: NCT03673475

Internal Jugular Vein Distensibility and Pleth Variability Index(PVI) for Evaluating Fluid Responsiveness

Assessment of intravascular volume status is crucial in order to predict the efficacy of volume status in major abdominal surgery. The aim of the study is to verify the feasibility and usefulness of the internal jugular vein distensibility index as an adjunct to the pleth variebility index(PVI) to predict fluid responsiveness in major abdominal surgery.

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Key information

Conditions

Intravascular Volume

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Tepecik Training and Research Hospital

Izmir, Turkey (Türkiye)

About this study

Forty patients above age 18 and ASA status I-III who are undergoing major abdominal surgery will be enrolled in the study. patients with right heart failure, arrythmia, severe valve stenosis or regurgitation will be excluded. After induction of general anesthesia, when the patients are hemodynamically stabilised, PVI and jugular vein distensibility will be calculated and recorded. after volume load with 500 ml gel infusion(in 15 min), measurements will be repeated within 10 minutes and recorded. Patients will be allocated to 2 groups according to the change in mean arterial pressure(MAP) after volume expansion: Responders will be defined as an increase in MAP by >%10; while nonresponders will be defined as an increase in MAP <%10 or decrease in MAP.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • American Society of Anesthesiologists(ASA) physical status I-III patients
  • patients undergoing major abdominal surgery

Exclusion criteria

  • arrythmia
  • severe right ventricle failure

Treatment and study plan

Assessment of fluid responsiveness

Procedure

assessment of intravascular volume status using pleth variebility index and internal jugular vein distensibility in major abdominal surgery

Primary outcomes

  1. number of patients with significant change in VJI distensibility and pleth variebility index

    Time frame: during surgery at day 0

    volume responders with significant change in jugular vein distensibility and pleth variebility index

Sponsors and collaborators

Lead sponsor

Tepecik Training and Research Hospital

Other

Registry information

Official study title

Internal Jugular Vein Distensibility and Pleth Variability Index for Evaluating Fluid Responsiveness

Important dates

Study start
2018
Primary completion
2018
Study completion
2018
First posted
Sep 17, 2018
Registry last updated
Nov 27, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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