Interferential Electrical Stimulation and Vasodilatation in Healthy Individuals

Interferential electrical stimulation (IES) increases local blood flow. It is not known whether increases in blood flow may be caused by inhibition of sympathetic activity, mediated by muscle metaboreflex activity. The purpose of this study was to evaluate the effect of IES on metaboreflex activation in healthy subjects.

Completed

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Key information

Conditions

Decreased Vascular Flow Behavior Motor Activity

Age range

18 year–40 year

Sex eligibility

All sexes

Study type

Observational

Primary location

University of Brasilia, Brasília, Federal District, Brazil

About this study

The study sample consisted of 11 healthy young individuals. All subjects were non-smokers, non-obese and free of any signs or symptoms of disease, as revealed by medical history, physical examination and electrocardiogram at rest and during cardiopulmonary exercise testing. Exclusion criteria were pregnancy, breast-feeding, alcohol or drug abuse, and any medication with potential effects on cardiovascular variables. Subjects were asked not to drink caffeine-containing drinks or exercise for at least 12 and 48 hours, respectively, before the experimental protocols.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Subjects are non-smokers
non-obese
and free of any signs or symptoms of disease

Exclusion criteria

Pregnancy
breast-feeding
alcohol or drug abuse
medication with potential effects on cardiovascular variables

Treatment and study plan

Interferential

Device

The individuals are treated acutely with IES during 30 min, providing a continuous flow of symmetrical rectangular interferential current biphasic pulses using bipolar electrodes with two channels and a slope of 1/5/1. The fixed current is adjusted to 4000 Hz, with the current AMF at 100 Hz and an AMF variation of 25 Hz (25% of AMF).

Other names: Transcutaenous electrical stimuation

Interferential Placebo

Device

The same instructions and electrode positions were provided to the placebo, although the equipment did not provide any stimulation current

Primary outcomes

Muscle Metaboreflex Reflex

Time frame: Participants will be followed for the duration of metaboreflex activity (up to 30 minutes)

Calf blood flow

Sponsors and collaborators

Lead sponsor

Hospital de Clinicas de Porto Alegre

Other

Collaborators

University of Brasilia

Registry information

Official study title

Interferential Electrical Stimulation Improves Peripheral Vasodilatation in Healthy Individuals: A Randomized Crossover Study

Acronym: InterM

Important dates

Study start: 2011
Primary completion: 2012
Study completion: 2012
First posted: Oct 12, 2011
Registry last updated: Jan 24, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed