Skip to main content
OpenTrials
Completed

NCT Number: NCT02851654

Interest of Eye Movement Measurements in the Comprehension of Dry Eyes Symptoms

Dry eye syndrome is a benign situation however its impact on patient's quality of live and on health system is not trivial. One problem is the lack of correlation between patient's symptoms and physical sign observed on slit lamp examination. Eye blinking is a parameter of increased interest in this pathology particularly its frequency. To date no treatment of dry eye syndrome has a proven impact on eye blinking frequency. However recording of blinks has mostly been performed on short duration (3 to 5 minutes) and the distribution of intervals between 2 blinks is not gaussian but exponential. In this study, it is proposed to use modern eye-movement recorder to measure the blink frequency on longer duration (12 minutes) while reading on a screen computer and during a face-to-face interview before and after treatment of meibomian gland dysfunction responsible of moderate to severe dry eye syndrome.

Completed

Looking for future studies?

Notify Me

Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Fondation Ophtalmologique Adolphe de Rothschild (FOR)

Paris, 75019, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Moderate to severe dry eye syndrome (Ocular Surface Disease Index> 30) following a meibomian gland dysfunction
  • Not yet properly treated for a meibomian gland dysfunction

Exclusion criteria

  • History of other ophthalmological or neurological disease
  • Pregnant or breastfeeding women
  • Patient under 18 years old
  • Patient under legal protection

Treatment and study plan

Infrared oculography

Device

The infrared oculography provides binocular recordings and allows simultaneous measurement of horizontal and vertical eye movements.

Primary outcomes

  1. duration between 2 blinks

    Time frame: 2 months after treatment

    Assessment by infrared oculography while the patient is reading on a computer screen and during a face-to-face interview

Sponsors and collaborators

Lead sponsor

Fondation Ophtalmologique Adolphe de Rothschild

Network

Registry information

Official study title

Interest of Eye Movement Measurements in the Comprehension of Dry Eyes Symptoms (BOSO)

Acronym: BOSO

Important dates

Study start
2014
Primary completion
2019
Study completion
2019
First posted
Aug 1, 2016
Registry last updated
Dec 11, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.