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OpenTrials
Completed

NCT Number: NCT02236273

Interactive, Health Literacy Promoting Text Messages and HPV Vaccine Completion In Minority Adolescents

Emerging communication technologies, such as text messaging offer low-cost, scalable opportunities to improve health literacy and promote healthy behaviors, such as vaccination. While the investigators reported the success of text message vaccine reminders, effects were limited by their untailored approach. The trans-theoretical model of behavior change supports tailoring interventions to an individual's stage of decision-making. Human papillomavirus (HPV) is the most prevalent sexually transmitted virus in the U.S. and can lead to genital warts, and cervical, anal and penile cancer. The three-dose vaccine is 90-100% efficacious. Minorities are at greatest risk for such cancers but have low HPV vaccine completion rates. Limited health literacy regarding the vaccine can affect series completion. The investigators will compare the effects of enhancing text message vaccination reminders with interactive, vaccine health literacy-promoting information tailored to vaccine decision making-stage on HPV vaccine series completion. The effects of these messages represent a new paradigm in interactive health communications.

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Key information

Conditions

Human Papillomavirus

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Columbia University Medical Center

New York, 10032, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Parenting adult of adolescent age 11-17 years
  • Adolescent received 1st dose of HPV at a study site within the last 2 weeks.
  • Eligible parent's cell phone has text message capability

Exclusion criteria

  • Language other than English or Spanish only
  • Parent already in the study
  • Intends to move away from the New York City area in <12 months

Treatment and study plan

Conventional text message reminder

Behavioral

Receipt of conventional text message notifying when due for next dose

Enhanced text message reminders

Behavioral

Receipt of enhanced text messages notifying when due for next dose coupled with educational information

Primary outcomes

  1. Number of Participants Who Completed HPV Vaccine Series

    Time frame: 12 months

    receipt of 3 doses of HPV vaccine by 12 months after initiation

Secondary outcomes

  1. Time Between 1st and 2nd Dose

    Time frame: 12 months

    Time elapsed in days between first and second dose- for those in need of three doses

  2. Time Between 1st and 3rd Dose

    Time frame: 12 months

    Time elapsed (in days) between 1st and 3rd dose for those in need of three doses

Sponsors and collaborators

Lead sponsor

Columbia University

Other

Collaborators

  • Agency for Healthcare Research and Quality (AHRQ)

Registry information

Official study title

Comparative Effectiveness of Interactive, Health Literacy Promoting Text Messages on HPV Vaccine Completion In Minority Adolescents

Important dates

Study start
2014
Primary completion
2017
Study completion
2017
First posted
Sep 10, 2014
Registry last updated
Jul 29, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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