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Completed

NCT Number: NCT01435837

Interaction of Caffeine and Hydration on Voice

The purpose of the study, Effects of Interaction of Caffeine and Hydration on Voice Performance, is to gather information about the effects of caffeine and hydration upon voice performance. The research question involves whether systemic hydration may reduce degradation on voice performance caused by caffeine ingestion. It is hypothesized that the hydration conditions will result in a less degraded vocal performance as compared with the nonhydration condition.The investigation involves abstention from any caffeine ingestion for 24 hours - from 8pm the day before testing to 8am the morning of testing. In addition, preparation for participation involves abstaining from ingesting any foods and liquids for 12 hours - from 8pm to 8am of the following morning. Each test will take about 10 minutes.

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Key information

Conditions

Voice Disorders Laryngeal Diseases Nervous System Diseases Neurologic Manifestations Otorhinolaryngologic Diseases Pathological Conditions, Signs and Symptoms Respiratory Tract Diseases Signs and Symptoms

Age range

18 year–35 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Early Phase 1

Primary location

Southern Illinois University Carbondale

Carbondale, Illinois, 62901, United States

About this study

The objective of this investigation is to explore the interaction of water and caffeine on voice performance through (a) acoustic measures of voice, and (b) aerodynamic measurements (minimum lung pressure required to initiate phonation. The acoustic and aerodynamic measurements were selected for this study in an effort to demonstrate the effects of four levels of hydration and caffeine status on voice quality: 1) caffeine and water1 (i.e.., Experimental Group 1 - ingestion of 200 mg of caffeine in conjunction with 500 ml of water), 2) caffeine and water2 (i.e., Experimental Group 2 - ingestion of 200 mg of caffeine in conjunction with 1.0 liter of water), 3)caffeine only (i.e., Experimental Group 3: ingestion of 200 mg of caffeine and no water), and 4) control (i.e. no ingestion of caffeine or water). The research question involves whether systemic hydration may reduce degradation on voice performance caused by caffeine ingestion. It is hypothesized that the hydration conditions will result in a less degraded vocal performance as compared with the nonhydration condition. Additionally, it is hypothesized that ingestion of 1.0 liter of water will have a greater effect on voice performance than ingestion of 500 ml of water. An additional objective of this study is to increase scientific knowledge of voice functioning by providing further data about the effect of the interaction of water and caffeine on voice performance. The results of this project may be a valuable addition to the scientific literature in vocology, and may also contribute to prevention plans for minimizing vocal disturbances. Therefore, vocational programs may include vocal prevention directions based on this study. In addition, knowledge about prevention of voice disorders may be included in the academic curriculum of students enrolled in training programs for professions involving substantial voice use.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy individuals, ranging from 18 to 35 years of age.

Exclusion criteria

  • History of voice disorders, history of coronary disease, history of high blood pressure.

Treatment and study plan

C2 (200mg of caffeine; 1/2 L of water)

Drug

200mg of caffeine (tablet); 1/2 of water

Other names: Caffeine and water 2.

C3(200mg of caffeine; 1 L of water)

Drug

Ingestion of 200 mg of caffeine and 1 Liter of water after between pretest and posttest.

Other names: Caffeine and water 3.

C1 (200mg of caffeine, no water)

Drug

Ingestion of 200mg of caffeine (tablet); no water ingestion.

Other names: Caffeine

Placebo (no caffeine, no water).

Drug

No ingestion of caffeine; no ingestion of water between pretest and posttest.

Other names: Control.

Primary outcomes

  1. Effect of caffeine and hydration on acoustic measures of voice.

    Time frame: 1 year

    The acoustic measurement of voice include the parameters of relative average perturbation (RAP), shimmer, and sound pressure level (SPL).

Secondary outcomes

  1. Effect of caffeine and hydration on aerodynamic measures of voice. Effect of caffeine and hydration on aerodynamic measures of voice.

    Time frame: 1 year

    The aerodynamic measurement of voice includes the parameter of airflow. Airflow measurements refer to the amount of air passing through the region of the vocal folds decibels.

Sponsors and collaborators

Lead sponsor

Southern Illinois University Carbondale

Other

Registry information

Official study title

Effects of the Interaction of Caffeine and Hydration on Voice Performance

Important dates

Study start
2010
Primary completion
2013
Study completion
2013
First posted
Sep 19, 2011
Registry last updated
Jun 11, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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