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Completed

NCT Number: NCT02902263

Inter-Hospital Transfer to a Vascular Neurology Unit After Telethrombolysis

Early thrombolysis is essential in treating ischemic strokes. The time window for thrombolysis is limited to 4,5 hours after symptoms onset.

In the French region of Franche Comté, in order to reduce the thrombolytic delay, a telemedicine network was developed between the neurovascular reference unit (NVU) localised in the University Hospital of Besançon and the peripheral hospital centres. Patients may then be transported to the NVU immediately after the thrombolysis initiation.

The aim of our study was to assess the relevance of a systematic medicalization of transfer to the NVU of patients with stroke who were telethrombolyzed before.

It was a retrospective, monocentric and observational study conducted over 24 months, in Franche-Comte (France).

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

CHRU Besancon

Besançon, 25030, France

About this study

Stroke is a major health problem with increasing incidence. It represents the leading cause of disability and the third cause of death in France. There are two main types of stroke: ischemic (80%) or hemorrhagic (20%).

Early thrombolysis is essential in treating ischemic strokes. The time window for thrombolysis is limited to 4,5 hours after symptoms onset.

In the French region of Franche Comté, in order to reduce the thrombolytic delay, a telemedicine network was developed between the neurovascular reference unit (NVU) localised in the University Hospital of Besançon and the peripheral hospital centres. Patients may then be transported to the NVU immediately after the thrombolysis initiation.

The aim of our study was to assess the relevance of a systematic medicalization of transfer to the NVU of patients with stroke who were telethrombolyzed before.

It was a retrospective, monocentric and observational study conducted over 24 months, in Franche-Comte (France). Evaluation of neurological status was made with the Glasgow score (GCS) and National Institute of Health Stroke Score (NIHSS). The respiratory (SpO2; needs O2) and hemodynamic status (arterial blood pressure, heart rate) were assessed as well as the need for medical resuscitation at different times of the transport (thrombolysis, transfer, arrival at the Regional University Hospital Centre).

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patient with ischaemic stroke
  • Emergency department admission between 01/01/2012 and 12/31/2013
  • Telemedicine stroke consult
  • Thrombolysis therapy
  • Patient transfered to NVU after thrombolysis initiation
  • Transfer staffed by a qualified physician

Exclusion criteria

  • Transfer non staffed by a qualified physician

Treatment and study plan

Primary outcomes

  1. Patient neurological status assessed by NIHSS score during transfer to NVU

    Time frame: one day

  2. Patient neurological status assessed by Glasgow score during transfer to NVU

    Time frame: one day

Secondary outcomes

  1. Patient respiratory status assessed by oxygen saturation

    Time frame: one day

  2. Patient hemodynamic status assessed by systolic and diastolic pressure

    Time frame: one day

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire de Besancon

Other

Registry information

Official study title

Inter-Hospital Transfer to a Vascular Neurology Unit After Telethrombolysis in France Comté

Acronym: TRATT

Important dates

Study start
2014
Primary completion
2015
Study completion
2016
First posted
Sep 15, 2016
Registry last updated
Jan 27, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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