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NCT Number: NCT07179718

Intensive Care Unit Rehabilitation Protocols

The aim of this study was to investigate the effects of NMES combination applied in addition to bicycle ergometry on mobility, functional status, muscle strength and hemodynamic responses in ICU patients.

Participants will:

* Exercise training will be performed using the bicycle ergometer method, under the supervision of a physiotherapist, for 30 minutes a day for 5 consecutive days, at the earliest stage when the patient is clinically stable. * The other group will perform a 30-minute quadriceps muscle NMES session applied with a 4-channel electrical stimulator for 5 consecutive days in addition to the bicycle ergometer. * Evaluations for both groups will be made on the first day of the study (before starting the exercise training) and at the end of the fifth day (after the exercise training).

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Critical Illness Disease Attributes ICU Patients Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Hacettepe University Medical Intensive Care Unit

Ankara, ALTINDAG, 06230, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age ≥ 18 years
  • Admitted to medical intensive care unit
  • Expected intensive care unit stay > 48 hours
  • Hemodynamically stable

Exclusion criteria

  • Severe neurological injury (e.g., acute stroke, spinal cord injury)
  • Terminal illness with palliative care decision
  • Severe orthopedic limitations preventing mobilization
  • Pregnancy

Treatment and study plan

Neuromuscular Electrical Stimulation

Device

Neuromuscular electrical stimulation (NMES) is a treatment method in which electrical conduction via surface electrodes is used to stimulate muscle contraction.

bicycle ergometer

Device

Exercise training will be performed using the bicycle ergometer method, under the supervision of a physiotherapist, for 30 minutes a day for 5 consecutive days, at the earliest stage when the patient is clinically stable.

Primary outcomes

  1. Change in Perme Intensive Care Unit Mobility Score over 5 days

    Time frame: 1st and 5th day of 5-day physiotherapy and rehabilitation after the patient is clinically stable

    The total score ranges from 0 to 32 points, with higher scores indicating better mobility and greater independence.

Sponsors and collaborators

Lead sponsor

Hacettepe University

Other

Registry information

Official study title

Effects of Two Different Rehabilitation Protocols on Mobility, Functional Status, Muscle Parameters, and Hemodynamic Responses in Intensive Care Patients

Acronym: ICU-Rehab

Important dates

Study start
2024
Primary completion
2026
Study completion
2026
First posted
Sep 18, 2025
Registry last updated
Sep 18, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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