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Completed

NCT Number: NCT04254120

Integrating Motivational Interviewing With Cognitive-behavioral Therapy

Cognitive-behavioral therapy (CBT) is efficacious for anxiety disorders and depression, but not all patients achieve remission, and dropout is considerable. Motivational interviewing (MI) may strengthen motivation to change, and influence non-response and dropout. Research shows that MI as a pretreatment to CBT produces moderate effects compared to CBT alone. Studies integrating MI with CBT (MI-CBT) throughout treatment are scarce. The present study explored the feasibility of MI-CBT in routine psychiatric care, and compared CBT alone to MI-CBT for anxiety disorders, depression, and unhealthy lifestyle behaviors. The Anxiety, Depression, Diet, Alcohol, Physical activity, and Tobacco (ADDAPT) feasibility study had a randomized controlled design, and data were analyzed using hierarchical regression.

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Key information

Conditions

Anxiety Disorders and Symptoms Anxiety Disorders Behavior Behavioral Symptoms Depression Life Style Mental Disorders

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

WeMind Psykiatri AB

Stockholm, SE-11357, Sweden

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 18 years of age or older
  • A principal diagnosis according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR) of panic disorder, social anxiety disorder, obsessive-compulsive disorder, generalized anxiety disorder, posttraumatic stress disorder, or major depressive disorder
  • At least one of the following unhealthy lifestyle behaviors: unhealthy eating habits, hazardous use of alcohol, insufficient physical activity, or tobacco use, according to screening criteria suggested by the National Board of Health and Welfare

Exclusion criteria

  • Psychotic symptoms
  • DSM-IV-TR criteria for substance abuse other than alcohol
  • DSM-IV-TR criteria for substance dependence including alcohol
  • Moderate to severe suicide risk according to the Mini-International Neuropsychiatric Interview or a score of 2 or above on item 9 on the Patient Health Questionnaire 9
  • Another simultaneous psychological treatment

Treatment and study plan

Cognitive-Behavioral Therapy

Behavioral

Psychological treatment focusing on changing cognitions and behaviors using information processing theory and learning theory approaches.

Integrated motivational interviewing and cognitive-behavioral therapy

Behavioral

Motivational interviewing is a psychological treatment approach focusing on increasing motivation by eliciting patient talk favoring behavior change and resolving patient ambivalence about change.

Primary outcomes

  1. Index measure of aggregated psychiatric symptoms

    Time frame: 12 weeks

    Symptoms of principal anxiety disorder or principal depression, expressed as z scores; higher scores indicate more severe symptoms

  2. Index measure of aggregated unhealthy lifestyle behaviors

    Time frame: 12 weeks

    Unhealthy lifestyle behaviors related to diet, physical activity, alcohol, or tobacco, expressed as z scores; higher scores indicate more problematic behaviors

Sponsors and collaborators

Lead sponsor

Karolinska Institutet

Other

Registry information

Official study title

Integrating Motivational Interviewing With Cognitive-behavioral Therapy for Anxiety Disorders, Depression, and Unhealthy Lifestyle Behaviors: a Feasibility Study

Important dates

Study start
2014
Primary completion
2014
Study completion
2015
First posted
Feb 5, 2020
Registry last updated
Sep 5, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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