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Completed

NCT Number: NCT03605043

Integrated Hypertension and HIV Care Cascades in Uganda

In this retrospective cohort study, we mapped the care cascades for both Hypertension and HIV within a HIV program in Uganda with the goal of identifying opportunities for developing contextually appropriate integrated care models, .

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Makerere University College of Health Sciences

Kampala, Central Region, +256, Uganda

About this study

Persons living with HIV (PLHIV) and receiving anti-retroviral therapy (ART) are at increased risk of cardiovascular disease (CVD) due to direct effects of ART and HIV infection itself, compounded by traditional CVD risk factors such as increased life expectancy and Westernized diet. Additionally, in sub-Saharan Africa, as is the case globally, hypertension (HTN) is a major risk factor for CVD. The prevalence of HTN in the setting of HIV reported in the literature is variable but may be higher than in the HIV-negative population.

World Health Organization (WHO) and Ugandan national HIV guidelines have recommended the integration of hypertension care into HIV programs since 2014 and 2016, but there has been limited uptake of this recommendation in practice. There have been successful efforts to integrate tuberculosis, malaria, nutrition, maternal-child health, and family planning into HIV programmes in Uganda. In this study, with the goal of identifying opportunities for developing contextually appropriate integrated care models, we mapped the care cascades for both HTN and HIV within a HIV program in Uganda.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 18 years of age and above, Having started Antiretroviral therapy between January 2014 and January 2017.

Exclusion criteria

  • PLHIV receiving treatment from clinics other than the 3 selected sites.

Treatment and study plan

Blood pressure management in the HIV program

Other

Integrated care for hypertension and HIV in the HIV program

Primary outcomes

  1. Blood pressure control

    Time frame: 1 year

    Blood pressure control among Persons living with both HIV and hypertension. Achieving Blood pressure of <140/90mmHg

Secondary outcomes

  1. HIV control

    Time frame: 1 year

    HIV control among persons living with both HIV and hypertension. Defined as HIV Viral suppression. Viral load of <1000 copies/mL

Sponsors and collaborators

Lead sponsor

Makerere University

Other

Registry information

Official study title

Integrated Hypertension and HIV Care Cascades in a HIV Treatment Program in Eastern Uganda: a Retrospective Cohort Study

Important dates

Study start
2014
Primary completion
2017
Study completion
2018
First posted
Jul 30, 2018
Registry last updated
Jul 30, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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