Insulin Resistance and Hypertensive Disorders in Pregnancy

The purpose of this study is to determine whether insulin resistance might affect the pathogenesis of hypertensive disorders in pregnancy since midtrimester. Furthermore, markers of vascular and placental injuries, of oxidative stress and inflammation will be evaluated.

Completed

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Key information

Conditions

Hypertension in Pregnancy Cardiovascular Diseases Diabetes Mellitus Diabetes Mellitus in Pregnancy Diabetes, Gestational Endocrine System Diseases Female Urogenital Diseases and Pregnancy Complications Glucose Metabolism Disorders Hyperinsulinism Hypertension Hypertension, Pregnancy-Induced Insulin Resistance Metabolic Diseases Nutritional and Metabolic Diseases Pre-Eclampsia Pregnancy Complications Urogenital Diseases Vascular Diseases

Age range

18 year–45 year

Sex eligibility

Female

Study type

Observational

Primary location

University Hospital

Messina, 98121, Italy

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

PCOS, BMI>/=30
previous pregnancy affected by hypertension or gestational diabetes
thrombophilia
Type I or II diabetes mellitus
autoimmune diseases
twin pregnancy
renal diseases
previous pre-eclampsia in relatives

Sponsors and collaborators

Lead sponsor

University of Messina

Other

Registry information

Official study title

The Role of Insulin Resistance in Gestational Hypertension and in Preeclampsia.

Important dates

Study start: 2006
Study completion: 2008
First posted: Dec 18, 2006
Registry last updated: Feb 18, 2009

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed