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Completed

NCT Number: NCT03385733

Inspiratory Muscle Training in Pulmonary Hypertension

The aim of this study is to investigate the effective of inspiratory muscle training on respiratory function, exercise capacity, physical activity and quality of life.

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Key information

Conditions

Pulmonary Hypertension Behavior Cardiovascular Diseases Hypertension Hypertension, Pulmonary Lung Diseases Motor Activity Respiratory Tract Diseases Vascular Diseases

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Istanbul University

Istanbul, 34010, Turkey (Türkiye)

About this study

Pulmonary hypertension (PH) is a condition which is seen with hemodynamic differences, pulmonary vascular resistance and right heart failure. Patients with pulmonary hypertension have, dyspnea, physical inactivity, reduced condition and respiratory muscle dysfunction. Aerobic exercise programs in patients with pulmonary hypertension are reported to result in improved exercise capacity and endurance of the patients, improvement in WHO functional class and quality of life, increased peak workload and increased peripheral muscle function. In recent years, few studies have investigated the efficacy of inspiratory muscle training in patients with PH.The aim of this study is to investigate the effective of inspiratory muscle training on respiratory function, exercise capacity, physical activity and quality of life.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Diagnosis of Pulmonary Hypertension,
  • NYHA functional class I-IV
  • MIP pressure <80 cm h2O

Exclusion criteria

  • COPD
  • Conditions which can limit the assessments
  • Insufficient cooperation

Treatment and study plan

Inspiratory Muscle Training

Other

The treatment group received IMT. Patients were trained using an inspiratory threshold-loading device

Primary outcomes

  1. mouth pressures

    Time frame: 10 minutes

    MIP and MEP

Secondary outcomes

  1. International Physical Activity Questionnaire-Short Form

    Time frame: 10 minutes

    Physical activity

  2. Minnesota Living with Heart Failure Questionnaire

    Time frame: 15 minutes

    quality of life

  3. Activity monitoring (Sense wear® Armband)

    Time frame: 3 days

    Metabolic holter

  4. 6 minute walking test

    Time frame: 15 minutes

    functional capacity

Sponsors and collaborators

Lead sponsor

Istanbul University

Other

Collaborators

  • Biruni University

Registry information

Official study title

The Effects of Inspiratory Muscle Training on Exercise Capacity, Physical Activity and Quality of Life in Pulmonary Hypertension

Important dates

Study start
2017
Primary completion
2018
Study completion
2018
First posted
Dec 28, 2017
Registry last updated
Mar 1, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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