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Completed

NCT Number: NCT03074435

Insecticide Resistance Management in Burkina Faso and Côte D'Ivoire

This study evaluates the benefit to use 1) insecticide residual sprayings, 2) larvicides, 3) Ivermectin for domestic animals and 4) behaviour change communication strategy to complement the universal coverage with LLINs through a cluster randomized trial.

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Key information

Conditions

Malaria Infections Mosquito-Borne Diseases Parasitic Diseases Protozoan Infections Vector Borne Diseases

Age range

Up to 21 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 3

Primary location

Institut de Recherche en Sciences de la Santé, Bobo-Dioulasso, Burkina Faso

Loading trial locations.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

For Cross-sectional surveys only, maximum age for participating in the study was 21 y/o in Côte d Ivoire and 18 y/o in Burkina Faso.

Treatment and study plan

Indoor residual sprayings

Device

Houses will be spayed with this formulation containing Pyrimiphos methyl.

Other names: Actellic

Larvicide

Device

Larval breeding sites will be treated with larvicide

BCC

Behavioral

Ivermectin

Biological

Primary outcomes

  1. Malaria incidence density

    Time frame: continuous monitoring during 2 years

    Malaria cases (whole population, every ages) registered in the local health system.

Secondary outcomes

  1. Entomological Inoculation Rate

    Time frame: Every 8 weeks during 2 years

    Number of infectious bites/personn

  2. Malaria prevalence

    Time frame: Every 4 months during 2 years

    % of positive blood smears among the 0-18 y/o population as recorded during cross sectional surveys.

Sponsors and collaborators

Lead sponsor

Institut de Recherche pour le Developpement

Other Gov

Collaborators

  • Institut Pierre Richet
  • Institut de Recherche en Sciences de la Sante, Burkina Faso

Registry information

Official study title

Insecticide Resistance Management in Burkina Faso and Côte D'Ivoire: Research on Vector Control Strategies

Acronym: REACT

Important dates

Study start
2016
Primary completion
2018
Study completion
2018
First posted
Mar 8, 2017
Registry last updated
Oct 1, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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