Moi University
Eldoret, Kenya
NCT Number: NCT02461628
The overall objective of this study is to evaluate the public health impact of targeted antimalarials subsidies through scale-up by determining the community-wide effects of targeting an antimalarial subsidy through a partnership between Community Health Volunteers (CHVs) and the private retail sector. The primary hypothesis to be tested is that offering a fixed-price voucher that reduces the cost for artemisinin combination therapy (ACT) purchase in the retail sector conditional on a positive malaria test (targeted subsidy) can improve uptake of testing for malaria and will increase the proportion of fevers tested for malaria before treatment. The study will be carried out in two sub-counties in Kenya with similar malaria burden but different access to health services; the investigators will use a cluster-randomized design to assign community units (CUs) in each sub-county to either an intervention or control arm. CHVs will be trained to use malaria rapid diagnostic tests (RDTs) to diagnose malaria in household members with documented or reported fever; households in intervention CUs will be informed of the intervention and encouraged to contact the CHV for any febrile illness in the home. There are minimal risks associated with receiving an RDT. Households with a positive RDT will be given a serialized voucher that will entitle the holder to purchase a quality assured ACT in the retail sector at a reduced, fixed price. The primary and secondary outcome measures will be compared at baseline and 12 months post-baseline through population-based surveying. The primary aim is to determine whether there is significant difference between the 2 study arms in the proportion of clients with fever who are tested prior to any treatment after adjusting for relevant covariates.
Looking for future studies?
Notify Me1 year and older
All sexes
Interventional
Not applicable
Eldoret, Kenya
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Intervention participation criteria:
Cross sectional survey participation criteria:
Exclusion criteria
Intervention exclusion criteria:
Cross sectional survey exclusion criteria:
Trained community health volunteers will offer eligible household members free malaria rapid diagnostic tests and a voucher allowing the purchase of a qualified ACT at a reduced fixed price in the retail sector conditional on a positive test
Time frame: 6 months, 12 months, 18 months
Time frame: 6 months, 12 months, 18 months
Time frame: 6 months, 12 months, 18 months
Time frame: 6 months, 12 months, 18 months
Denominator is all those who took AL. Artemether lumefantrine is one type of ACT.
Time frame: 6 months, 12 months, 18 months
The number of people with fever that report receiving correct treatment with regards to malaria (i.e., received an RDT test and took ACTs if the result was positive, or did not take ACTs if the test result was negative).
Duke University
Other
Innovative Partnership to Target Antimalarial Subsidies in the Retail Sector
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT03399318
Body Temperature Changes, Coma
Blantyre, Malawi
View Trial DetailsNCT01403350
Acute Febrile Illness, Body Temperature Changes
Jalalabad, Nangarhar, Afghanistan
View Trial DetailsNCT00367380
Anemia, Body Temperature Changes
Cali, Valle del Cauca Department, Colombia
View Trial DetailsNCT03523182
Bacterial Infections and Mycoses, Body Temperature Changes
Mansa, Luapura, Zambia
View Trial Details