Inhibitory Receptors in Eosinophils of Atopic Subjects

The purpose of this study is to analyze the expression and activity of inhibitory molecules on eosinophils obtained from allergic subjects.

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Key information

Conditions

Atopy Allergic Rhinitis Asthma Atopic Dermatitis Bronchial Diseases Congenital, Hereditary, and Neonatal Diseases and Abnormalities Dermatitis Dermatitis, Atopic Food Allergy Food Hypersensitivity Genetic Diseases, Inborn Hypersensitivity Hypersensitivity, Immediate Immune System Diseases Lung Diseases Lung Diseases, Obstructive Nose Diseases Otorhinolaryngologic Diseases Respiratory Hypersensitivity Respiratory Tract Diseases Rhinitis Rhinitis, Allergic Skin Diseases Skin Diseases, Eczematous Skin Diseases, Genetic Skin and Connective Tissue Diseases

Age range

20 year–60 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Meir Medical Center. Unit of Allergy and Clinical Immunology

Kfar Saba, Israel

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

age 20-60 years
a physician-diagnosed atopic disease

Exclusion criteria

atopic disease not active
steroid treatment
active non-atopic inflammatory disease, including infections
pregnancy

Treatment and study plan

Primary outcomes

Expression of surface molecules on eosinophils as assessed by flow cytometry

Time frame: December 2013

Blood samples from donors will be stained and evaluated by flow cytomtery

Sponsors and collaborators

Lead sponsor

Meir Medical Center

Other

Registry information

Official study title

Characterization of the Expression and Activity of Inhibitory Receptors Such as CLM-1 in Eosinophils of Atopic Subjects

Important dates

Study start: 2012
Primary completion: 2013
Study completion: 2013
First posted: Dec 9, 2011
Registry last updated: Mar 22, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed