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OpenTrials
Completed

NCT Number: NCT02297646

Influencing Factors on Training Efficacy in Healthy Adults

The purpose of this study is to investigate the effects of carbohydrate intake on training efficacy and health parameters of an endurance training program in healthy adults.

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Key information

Age range

30 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Early Phase 1

Primary location

Institute of Sports and Preventive Medicine, Saarland University

Saarbrücken, Saarland, 66012, Germany

About this study

Carbohydrate availability in endurance exercise seems to attenuate exercise-induced perturbations of cellular homeostasis and consequently diminishes the stimulus for training adaptation. Therefore, a negative relationship with exercise efficacy seems plausible. However, experimental evidence is rare and far from conclusive. Therefore, the present study aims to test the influence of carbohydrate intake on the efficacy of a typical preventive training program.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • no diseases
  • nonsmoker
  • BMI 25-30 kg/m²
  • blood pressure <160/100 mm/Hg
  • unmedicated
  • untrained status
  • V̇O2max < 50 mL/kg/min

Treatment and study plan

Endurance training

Behavioral

Other names: 4 sessions a week at 70 percent heart rate reserve

Primary outcomes

  1. Maximum oxygen consumption (VO2max)

    Time frame: 24 weeks

    VO2max

Secondary outcomes

  1. Numerous serum parameters from venous blood (LDL, HDL, Cholesterol, Triglycerides)

    Time frame: 24 weeks

    cardiovascular parameters:

    • LDL
    • HDL
    • Cholesterol
    • Triglycerides
  2. Resting heart rate

    Time frame: 24 weeks

  3. Resting blood pressure

    Time frame: 24 weeks

  4. Body fat (Skinfold thickness)

    Time frame: 24 weeks

    Skinfold thickness

  5. Ventilatory anaerobic threshold (VT)

    Time frame: 24 weeks

    VT

Sponsors and collaborators

Lead sponsor

Universität des Saarlandes

Other

Registry information

Official study title

The Influence of Carbohydrates on Training Efficacy and Health Status in Healthy Adults

Acronym: CHO

Important dates

Study start
2012
Primary completion
2013
Study completion
2013
First posted
Nov 21, 2014
Registry last updated
Nov 21, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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