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Completed

NCT Number: NCT05934734

Influence of Thoracic Outlet Syndrome Severity on Upper Extremity Function and Neural Integrity

The purpose of this study is to investigate the relationship between the severity of thoracic outlet syndrome and upper extremity function, as well as neural integrity.

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Key information

Conditions

Thoracic Outlet Syndrome Cardiovascular Diseases Nerve Compression Syndromes Nervous System Diseases Neuromuscular Diseases Peripheral Nervous System Diseases Vascular Diseases

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Outpatient clinic of faculty of physical therapy, Ahram Canadian University

Al Ḩayy Ath Thāmin, Giza Governorate, 3221405, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 18-65 years
  • Diagnosed with thoracic outlet syndrome
  • Willing and able to provide informed consent

Exclusion criteria

  • History of upper extremity surgery unrelated to thoracic outlet syndrome
  • Other upper extremity disorders unrelated to thoracic outlet syndrome

Treatment and study plan

No intervention

Other

This is an observational cross-sectional study. No intervention will be provided. Participants will be assessed and stratified into four cohorts based on self-reported symptom severity of thoracic outlet syndrome using a visual analog scale (VAS) to investigate the relationship between symptom severity and upper extremity function/neural integrity.

Primary outcomes

  1. Range of Motion (ROM) of the Shoulder joint

    Time frame: Baseline

    Active and passive ROM will be measured using a standard goniometer.

  2. Range of Motion (ROM) of the Elbow joint

    Time frame: Baseline

    Active and passive ROM will be measured using a standard goniometer.

  3. Range of Motion (ROM) of the Wrist joint

    Time frame: Baseline

    Active and passive ROM will be measured using a standard goniometer.

  4. Isometric Muscle Strength of shoulder

    Time frame: Baseline

    Maximum voluntary isometric strength of shoulder muscles will be measured using a handheld dynamometer.

  5. Isometric Muscle Strength of elbow

    Time frame: Baseline

    Maximum voluntary isometric strength of elbow muscles will be measured using a handheld dynamometer.

  6. Isometric Muscle Strength of wrist

    Time frame: Baseline

    Maximum voluntary isometric strength of wrist muscles will be measured using a handheld dynamometer.

  7. Self-reported upper extremity function

    Time frame: Baseline

    The Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire, developed by the Institute for Work and Health, is used to measure patient-reported functional outcomes. The DASH questionnaire consists of 30 questions regarding limitations to complete physical activities due to upper extremity pain/impairment. Participants will be asked to respond to each question based on their experiences over the preceding week according to a 5-point Likert scale ranging from 1 (no difficulty) to 5 (unable to do). Responses will be scored out of 5 and averaged to produce a score out of 100 with higher scores representing greater disability.

  8. Nerve Conduction Studies of ulnar nerve

    Time frame: Baseline

    Nerve conduction studies will assess the function/integrity of the ulnar nerve.

Sponsors and collaborators

Lead sponsor

Ahram Canadian University

Other

Registry information

Official study title

The Influence of Thoracic Outlet Syndrome Severity on Upper Extremity Function and Neural Integrity: A Cross-Sectional Study

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
Jul 7, 2023
Registry last updated
Jun 4, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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