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Completed

NCT Number: NCT03650179

Influence of the Urine Stream Interruption Exercise on the Micturition

This study assess micturition characteristic during and after a urine stream interruption exercise in patient without neurological or urologic disease.

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Key information

Conditions

Age range

18 year and older

Sex eligibility

Female

Study type

Observational

Primary location

Department of Neuro-urology, Tenon hospital

Paris, 75020, France

About this study

Urine stream interruption during voluntary voiding is often performed by women as a pelvic floor muscle exercise to develop urinary strength and avoid urinary incontinence. To our knowledge, there is no recommendation for performing urine stream interruption. Without evidence based data, stooping the urinary flow is reported as a risk of post void residual and urinary infection. The experts did not recommended to practice urine stream interruption as a pelvic floor exercise in urinary incontinence. However, during pelvic floor muscle training for urinary incontinence, exercises of urine stream interruption are often performed without knowledge of their consequences. The aim of this study is to assess micturition characteristic during and after a urine stream interruption exercise.

In this study, the investigators will compare the two uroflowmetries usually done in a Neuro-urology department of a University Hospital. Patient without neurological or urologic disease, consulting for a global evaluation of functional digestive disease and performing an urodynamic study will be included. During the urodynamic evaluation, two uroflowmetries are performed : one conventional uroflowmetry complying with the International Continence Society (ICS) recommendations and one uroflowmetry during exercise of urine stream interruption, as usually done in the department. Each uroflowmetry will be performed when the patient will feel a ''normal'' desire to void. For the urine stream interruption micturition, patients will be asked to "begin the micturition, stop at 3 seconds of micturition, when the stream is interrupt, start again voiding, again stop at 3 seconds of micturition and repeat this maneuver until the end of the micturition". As usual, sonographic estimation of post-void residual volume will complete each uroflowmetry.

The investigators will compare the voiding volume, the post-void residual volume, the maximal flow rate, the time to reach the maximal flow rate, the voiding time and the slope of the uroflowmetry (corresponding to the flow velocity acceleration) between the two uroflowmetries. For each voiding sequence of the urine stream interruption micturition the following parameters will be reported and compared: voiding volume and duration, maximal flow rate, time to reach the maximal flow rate, the latency to restart the micturition between each voiding sequence and the slope of the uroflowmetry.

Statistical analysis will be carried out using R 3.2.3 software (R Development Core Team, http://www.R-project.org) and R studio version 1.0.136. Differences between the two uroflowmetries will be evaluated using Student test. Correlation between the place of the voiding sequence in the urine stream interruption micturition and the different parameters will be evaluated using Pearson's correlations.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • follow in neuro-urology for functional digestive disease
  • Appointment for urodynamic assessment

Exclusion criteria

  • urological or neurological disease

Treatment and study plan

Observational study : No intervention

Other

Observational study : No intervention. Only exporting data

Primary outcomes

  1. post-void residual volume

    Time frame: 1 Day : during the urodynamic assessment

    comparison between post-void residual volume during normal micturition and exercise of urine stream interruption

Secondary outcomes

  1. maximal flow rate

    Time frame: 1 Day : during the urodynamic assessment

    comparison between maximal flow rate during normal micturition and exercise of urine stream interruption

  2. time to reach the maximal flow rate

    Time frame: 1 Day : during the urodynamic assessment

    comparison between time to reach maximal flow rate during normal micturition and exercise of urine stream interruption

  3. voiding time

    Time frame: 1 Day : during the urodynamic assessment

    comparison between the voiding time during normal micturition and exercise of urine stream interruption

  4. the slope of the uroflowmetry (corresponding to the flow velocity acceleration)

    Time frame: 1 Day : during the urodynamic assessment

    comparison between the slope of the uroflowmetry during normal micturition and exercise of urine stream interruption

Sponsors and collaborators

Lead sponsor

Pierre and Marie Curie University

Other

Registry information

Important dates

Study start
2018
Primary completion
2018
Study completion
2018
First posted
Aug 28, 2018
Registry last updated
Sep 25, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.