Influence of Paternal Age on Assisted Reproduction Outcome

In the recent years, there is an increasing tendency to the parenthood delay in developed countries, and there is not enough information available regarding the influence of the male's age on fertility. If any, the negative impact should be acting at advanced ages.

Our aim with this work was to determine the role of paternal age on IUI results embryo quality and IVF outcome. Evenmore, in order to standardize the female factor, good quality oocytes (from fertile oocyte donors) and only first IVF cycles in young women were considered.

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Key information

Conditions

We Will Retrospectively Assess Our Databases in Our Clinic From January 2000 to December 2006 IUI Standard IVF/ICSI Cycles and Ovum Donation IVF/ICSI Cycles Instituto Valenciano de Infertilidad in Valencia (Spain) Searching for Assisted Reproduction Procedures Who Were Referred to Our Unit to Cryopreserve Sperm During the Period

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

IVI

Valencia, 46015, Spain

About this study

A retrospective study has been designed with a total number of 2204 IUI, 1286 IVF cycles and 1412 IVF cycles with donated oocytes from 2000 to 2006.

The inclusion criteria will be for IUI: women under 38 years old, tubal patency demonstrated by hysterosalpingography, normal uterine scan, normal basal hormonal levels, body mass index < 27 kg/m2, and absence of polycystic ovarian syndrome and endometriosis. For normal IVF cycles and oocyte donation cycles only first cycles will be analyzed. Cycles will be studied only in couples with absence of severe male factor.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

women under 38 years old, tubal patency demonstrated by hysterosalpingography, normal uterine scan, normal basal hormonal levels, body mass index < 27 kg/m2.

Exclusion criteria

absence of polycystic ovarian syndrome, hydrosalpinx or endometriosis.
Cycles were studied only in couples with absence of severe male factor.

Sponsors and collaborators

Lead sponsor

Instituto Valenciano de Infertilidad, IVI VALENCIA

Other

Registry information

Acronym: MALE AGING

Important dates

Study start: 2007
Study completion: 2007
First posted: Aug 2, 2007
Registry last updated: Apr 28, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.