Influence of Nutrition on Nasal and Bronchial Affliction in Patients With Allergy on Grass-Pollen

The study is meant to observe the influence of nutrition on nasal and bronchial discomfort in patients with allergy on grass pollen after specific bronchial provocation. Therefore, the investigators will record the patients' nutrition habits and measure the blood level of long chained polyunsaturated fatty-acids.

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Key information

Conditions

Bronchial Hyperreactivity Allergy Asthma Bronchial Asthma Bronchial Diseases Hypersensitivity Hypersensitivity, Immediate Immune System Diseases Lung Diseases Lung Diseases, Obstructive Respiratory Hypersensitivity Respiratory Tract Diseases

Age range

12 year–45 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Goethe University, Department of Pulmonology

Frankfurt am Main, Hesse, 60590, Germany

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

age >12 and <45 years
informed consent
Known allergy on grass-pollen

Exclusion criteria

age <12 and >45 years
Clinical asthma requiring regular inhalation
vital capacity >80%
FEV1 < 75%
Chronic disease
pregnancy
Inhalative or systemic steroid use
substance abuse
incapability of understanding the study's purpose and performance

Treatment and study plan

inhalative specific bronchial provocation with grass-pollen

Other

Primary outcomes

correlation of the blood fatty-acid level and bronchial hyperreactivity, measured as the exhaled NO.

Time frame: aug 2006 - feb 2007

Sponsors and collaborators

Lead sponsor

Johann Wolfgang Goethe University Hospital

Other

Registry information

Official study title

Influence of Nutrition on Nasal and Bronchial Affliction in Patients With Allergy on Grass-Pollen After Low-Dosed Specific Bronchial Provocation

Important dates

Study start: 2006
Primary completion: 2008
Study completion: 2008
First posted: Aug 23, 2007
Registry last updated: Feb 4, 2009

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed