Skip to main content
OpenTrials
Completed

NCT Number: NCT00832663

Influence of Non-steroidal Anti-inflammatory Drugs (NSAID) on Muscle Regeneration

The purpose of this study is to determine the influence of non-steroidal anti-inflammatory drugs (NSAIDs) on muscle regeneration.

The investigators' hypothesis is that ingestion of NSAID will delay or impair muscle regeneration.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Muscle Damage

Age range

18 year–35 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Bispebjerg Hospital

Copenhagen, NV, 2400, Denmark

About this study

The model employed to induce muscle damage is electrical stimulation. Muscle biopsies will be examined to follow the response of satellite cells and muscle regeneration. Study participants will be randomly assigned to a placebo or NSAID group in a double-blinded manner.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • male
  • healthy
  • does not exercise regularly

Exclusion criteria

  • displays contraindications for taking NSAID
  • well-trained

Treatment and study plan

NSAID

Drug

Effect of NSAID ingestion on muscle regeneration

Placebo

Drug

receive placebo

Primary outcomes

  1. Muscle regeneration

    Time frame: 1 month

Secondary outcomes

  1. Muscle strength

    Time frame: 1 month

Sponsors and collaborators

Lead sponsor

Bispebjerg Hospital

Other

Collaborators

  • Anti Doping Danmark
  • Danish Ministry of Culture
  • King Christian IX and Queen Louise Jubilee Bursary
  • Lundbeck Foundation
  • Team Denmark
  • The Danish Rheumatism Association

Registry information

Official study title

The Influence of Blocking Inflammatory Activity in Vivo on Skeletal Muscle Regeneration in Humans

Important dates

Study start
2009
Primary completion
2009
Study completion
2009
First posted
Jan 30, 2009
Registry last updated
Mar 16, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.