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Completed

NCT Number: NCT01849211

Influence of Neuromuscular Block on Mask Ventilation

Difficult mask ventilation might lead to a life-threatening situation, if endotracheal intubation is also impossible and neuromuscular blocking agents (NMBA) inhibit spontaneous ventilation. However, controversies exist if NMBA improve or impede face mask ventilation. Therefore, the effect of NMBAs on mask ventilation is assessed in patients with predictors for difficult face mask ventilation.

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Key information

Conditions

Effect of a Neuromuscular Block on Ventilation Pathologic Processes Pathological Conditions, Signs and Symptoms Respiration Disorders Respiratory Aspiration Respiratory Tract Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

KKH Dormagen

Dormagen, 71375, Germany

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with risk factors for difficult face mask ventilation
  • Patients scheduled for general anaesthesia with endotracheal intubation

Exclusion criteria

  • Increased Risk for pulmonary aspiration
  • scheduled for awake fiberoptic intubation
  • pregnancy

Treatment and study plan

Rocuronium

Drug

Primary outcomes

  1. minute volume

    Time frame: 15 min (from Induction of anaesthesia until onset of NMBA )

Secondary outcomes

  1. incidence of difficult mask ventilation - tidal volume < 150 ml

    Time frame: 15 min

Other outcomes

  1. airway pressure

    Time frame: 15 min

    measurement of peak airway pressure

Sponsors and collaborators

Lead sponsor

Kreiskrankenhaus Dormagen

Other

Registry information

Official study title

Influence of a Neuromuscular Block on Face Mask Ventilation Conditions During Induction of Anaesthesia

Important dates

Study start
2013
Primary completion
2017
Study completion
2018
First posted
May 8, 2013
Registry last updated
Feb 21, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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