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OpenTrials
Completed

NCT Number: NCT01734759

Influence of Medication Taste on Pediatric Prescribers' Prescribing Habits

The purpose of this study is to see if a medication taste test influences the prescribing habits of pediatric prescribers at Mayo Clinic.

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Key information

Conditions

Healthy

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 1

Primary location

Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • subjects possess prescriptive authority (e.g. MD, nurse practitioner, physician's assistant, medication therapy management pharmacists)
  • subjects have prescribed at least one of the study medications from one of the medication classes to pediatric patients at an outpatient clinic in the three months preceding the study

Exclusion criteria

  • subjects do not prescribe any of the tested medications
  • subject has an allergy to all of the study medications
  • subject is pregnant or breastfeeding
  • subject has a medical condition that prevents them from being involved in the taste test

Participants are advised to be within or accessible to the Rochester, MN area during study recruitment and accessible afterwards via mail, email or fax.

Treatment and study plan

Taste Test

Drug

Before the taste test each participant will fill out an informed consent form and an enrollment survey. Each participant will receive 0.5 mL of each study medication in the taste test. During the taste test each medication in a class will be labeled with a color name so as to prevent any bias from preconceived taste perception. They will record their perception of the medications taste on a visual analog scale (VAS). An anaphlyaxis kit will be on hand in case of emergencies. Between samples participants will cleanse their palate with a saltine cracker and 30 mL of water. 5 different classes of medications will be tested.

Medications to be sampled and the corresponding dose of the test dose are:

  • Cephalosporins: cefdinir 12.5 mg, cefixime 10 mg
  • Penicillins: penicillin VK 12.5 mg, amoxicillin 12.5 mg
  • Analgesic/antipyretics: acetaminophen 16 mg, ibuprofen 10 mg
  • Steroids: prednisolone 1.5 mg, prednisone 0.5 mg
  • H2 receptor blockers: famotidine 4 mg, ranitidine 7.5 mg

Primary outcomes

  1. Taste scores on the visual analog scale

    Time frame: Change from baseline in taste scores at 3 months

    Medication taste scores on the visual analog scale before and after a medication tasting will be measured.

Sponsors and collaborators

Lead sponsor

Mayo Clinic

Other

Registry information

Official study title

Influence of Medication Palatability on Prescribing Habits of Pediatric Prescribers

Important dates

Study start
2012
Primary completion
2013
Study completion
2013
First posted
Nov 28, 2012
Registry last updated
Oct 21, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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